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Anti-Corticotropin Releasing Factor antibody (ab8901)

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Overview

Product name

Anti-Corticotropin Releasing Factor antibody
See all Corticotropin Releasing Factor products (8) ...

Description

Rabbit polyclonal to Corticotropin Releasing Factor

Tested applications

ICC, RIA, WB, IHC-Pmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide, corresponding to amino acids 1-41 of Rat Corticotropin Releasing Factor.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Liquid antiserum

Purity

Whole antiserum

Clonality

Polyclonal

Isotype

IgG

Research areas

Neuroscience >> Endocrine system >> Hypothalamic pituitary adrenal axis
Signal Transduction >> Growth Factors/Hormones >> Hormones
Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones

Applications

Show applications key

Our Abpromise guarantee covers the use of ab8901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    AP

     AP: Use at an assay depe...Read more →

    AP: Use at an assay dependent concentration.

  • ICC

     ICC: 1/1000

    ICC: 1/1000

  • RIA

     RIA: 1/600000

    RIA: 1/600000

  • WB

     WB: 1/10000

    WB: 1/10000

  • IHC-P

    Three stars (1 Abreview) IHC-P: 1/200 - 1/600.

    IHC-P: 1/200 - 1/600.

Target

Relevance

CRF precursor is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRF is a neuroendocrine hormone secreted by the paraventricular nucleus (PVN) of the hypothalamus and is a key player in the hypothalamic pituitary adrenal axis. It is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. Neuronal CRF is important in a variety of diverse roles including, memory, depression, stress, kidney function, parturition, metabolism and feeding (to mention a few).

Cellular localization

Secreted

Alternative names

  • Corticoliberin antibody
  • Corticoliberin precursor antibody
  • Corticotropin releasing factor antibody
  • Corticotropin releasing hormone antibody
  • Corticotropin releasing hormone deficiency included antibody
  • crf antibody
  • crh antibody
  • crh deficiency included antibody
see all

Database links

References for Anti-Corticotropin Releasing Factor antibody (ab8901)

This product has been referenced in:

  • García-Moreno Fet al. A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. Nat Neurosci 13:680-9 (2010). IHC-P; Mouse.Read more (PubMed: 20495559) »
  • Ruggeri RMet al. Immunohistochemical localization and functional characterization of somatostatin receptor subtypes in a corticotropin releasing hormone- secreting adrenal phaeochromocytoma: review of the literature and report of a case. Eur J Histochem 53:1-6 (2009). IHC-P; Human.Read more (PubMed: 19351607) »

See all 4 publications for this product

Publishing research using ab8901? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"