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Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

MSCatalog No. MS1029

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Overview

Product name

Anti-Ctip2 antibody [25B6] (FITC)
See all Ctip2 products (7) ...

Description

Rat monoclonal [25B6] to Ctip2 (FITC)

Conjugation

FITC

Conjugation notes

Fluorochrome/Protein Ratio: at least 3 moles FITC per mole of IgG.

Tested applications

WB, ICC, Flow Cytmore details

Cross reactivity

Reacts with

Mouse, Human, Zebrafish

Immunogen

Protein fragment, corresponding to amino acids 1-150 of Human Ctip2.

Positive control

Jurkat cells.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Store in the dark. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA

Concentration

Concentration information loading...

Purity

Ammonium Sulphate Precipitation

Purification notes

Purity is near homogeneity as judged by SDS-PAGE. ab123449 was produced in vitro using hybridomas grown in serum-free medium, and then concentrated by ammonium sulfate precipitation.

Clonality

Monoclonal

Clone number

25B6

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HAT
Epigenetics and Nuclear Signaling >> Transcription >> Transcription Factors
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neural Signal Transduction
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> Zinc Finger
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation

  • Immunocytochemistry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)Immunocytochemistry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449) image (enlarge)

  • Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449) image (enlarge)

  • Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab123449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.

Tissue specificity

Highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma.

Sequence similarities

Contains 6 C2H2-type zinc fingers.

Cellular localization

Nucleus.

Target information above from: UniProt accessionQ9C0K0 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • B cell lymphoma/leukemia 11B antibody
  • B-cell CLL/lymphoma 11B antibody
  • B-cell lymphoma/leukemia 11B antibody
  • BC11B_HUMAN antibody
  • BCL-11B antibody
  • Bcl11b antibody
  • COUP-TF interacting protein 2 antibody
  • COUP-TF-interacting protein 2 antibody
  • Ctip 2 antibody
  • hRit1 antibody
  • MS1029 antibody
  • Radiation induced tumor suppressor gene 1 antibody
  • Radiation induced tumor suppressor gene 1 protein antibody
  • Radiation-induced tumor suppressor gene 1 protein antibody
  • Rit 1 antibody
  • Rit1 antibody
see all

Database links

Anti-Ctip2 antibody [25B6] (FITC) images:

  Immunocytochemistry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

Immunocytochemistry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

ab123449 at 0.125µg/ml staining CTIP2 in Jurkat cells by Immunocytochemistry. (N.B. cells were stained for 2h at room temperature in 3% BSA blocking solution.)

  Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

ab123449 at 0.125µg/ml staining Ctip2 in Jurkat cells by Flow Cytometry (red) or an equal amount of an FITC conjugated control antibody (black) in 3% BSA block.The Jurkat cells show a clear CTIP2 specific signal

  Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

Flow Cytometry - Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

ab123449 at 0.125µg/ml staining Ctip2 in SH-SY5Y cells by Flow Cytometry (red) or an equal amount of an FITC conjugated control antibody (black) in 3% BSA block. The SH-SY5Y cells do not show significant CTIP2 signal over the negative control signal.

References for Anti-Ctip2 antibody [25B6] (FITC) (ab123449)

ab123449 has not yet been referenced specifically in any publications.

Publishing research using ab123449? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"