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Product name
Anti-Cyclin A antibody [BF683]
See all Cyclin A products (20) ...
Description
Mouse monoclonal [BF683] to Cyclin A
Tested applications
WB, IPmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein (Human)
Epitope
ab28282 reacts with an epitope located upstream of the cyclin box.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.08% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Purification notes
Purified IgG1.
Clonality
Monoclonal
Clone number
BF683
Isotype
IgG1
Research areas
Cardiovascular >> Lipids / Lipoproteins >> Lipoproteins/Apolipoproteins >> Apolipoproteins
Cancer >> Cell cycle >> Cyclins >> Cyclin A family
Epigenetics and Nuclear Signaling >> Cell cycle >> Cyclins >> Cyclin A Family
Cell Biology >> Cell Cycle >> Cyclins >> Cyclin A Family
Cell Biology >> Cell Cycle >> Cyclins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab28282 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 49 kDa.
IP: Use at an assay dependent dilution.
Target
Function
Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
Sequence similarities
Belongs to the cyclin family. Cyclin AB subfamily.
Developmental stage
Accumulates steadily during G2 and is abruptly destroyed at mitosis.
Cellular localization
Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER.
Target information above from: UniProt accessionP20248
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CCN1 antibody
- CCNA antibody
- CCNA antibody
see all
Database links
- Entrez Gene: 890 Human
- Omim: 123835 Human
- SwissProt: P20248 Human
- Unigene: 58974 Human
References for Anti-Cyclin A antibody [BF683] (ab28282)
This product has been referenced in:
- Davis ST et al. Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science 291:134-7 (2001).Read more (PubMed: 11141566) »
See 1 publication for this product
Publishing research using ab28282? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"