Anti-Cyclin A antibody [E72.1] (ab18506)
Overview
- Product nameAnti-Cyclin A antibody [E72.1]See all Cyclin A primary antibodies ...
- DescriptionMouse monoclonal [E72.1] to Cyclin A
- Tested applicationsIHC-Fr, IP more details
- Species reactivityReacts with: Mouse, Rat, Cow, Human
- Immunogen
Full length native protein (purified) (Cow).
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: PBS -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Monoclonal
- Clone numberE72.1
- IsotypeIgG1
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab18506 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| IHC-Fr | IHC-Fr: Use at an assay dependent dilution. |
| IP | IP: Use at an assay dependent dilution. |
Target
- FunctionEssential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
- Sequence similaritiesBelongs to the cyclin family. Cyclin AB subfamily.
- Developmental stageAccumulates steadily during G2 and is abruptly destroyed at mitosis.
- Cellular localizationNucleus. Cytoplasm. Cytoplasmic when associated with SCAPER.
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Database links
- Entrez Gene: 281667 Cow
- Entrez Gene: 890 Human
- Entrez Gene: 12428 Mouse
- Entrez Gene: 114494 Rat
- Omim: 123835 Human
- SwissProt: P20248 Human
- SwissProt: P51943 Mouse
- Unigene: 58974 Human
- Unigene: 4189 Mouse
- Unigene: 13094 Rat
see all
Target information above from: UniProt accession
P20248
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- CCN1 antibodyCCNA antibodyCCNA antibody
- CCNA2 antibodyCCNA2_HUMAN antibodyCyclin A2 antibodyCyclin-A antibodyCyclin-A2 antibody
see all
References for Anti-Cyclin A antibody [E72.1] (ab18506)
This product has been referenced in:
- Garner AP et al. Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint. Oncogene 21:8089-104 (2002). Read more (PubMed: 12444545) »
- Bashir T et al. Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model. Proc Natl Acad Sci U S A 97:5522-7 (2000). Read more (PubMed: 10792046) »
