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Anti-Cyclin A antibody (ab2097)

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Overview

Product name

Anti-Cyclin A antibody
See all Cyclin A products (20) ...

Description

Rabbit polyclonal to Cyclin A

Specificity

Antiserum will specifically react with a 60 kDa Cyclin A protein. No reaction was observed against other related cyclins.

Tested applications

WB, IP, ELISA, ICC/IFmore details

Cross reactivity

Reacts with

Mouse, Rat, Rabbit, Human

Immunogen

Fusion protein (Human).

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.01% Sodium Azide

Purity

Whole antiserum

Purification notes

This product was prepared from monospecific antiserum by delipidation and defibrination.

Clonality

Polyclonal

Isotype

IgG

Research areas

Cardiovascular >> Lipids / Lipoproteins >> Lipoproteins/Apolipoproteins >> Apolipoproteins
Cancer >> Cell cycle >> Cyclins >> Cyclin A family
Epigenetics and Nuclear Signaling >> Cell cycle >> Cyclins >> Cyclin A Family
Cell Biology >> Cell Cycle >> Cyclins >> Cyclin A Family
Cell Biology >> Cell Cycle >> Cyclins

Applications

Show applications key

Our Abpromise guarantee covers the use of ab2097 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • WB

     

  • IP

     

  • ELISA

     

  • ICC/IF

     

Application notes

ELISA: 1/500 - 1/2000.
ICC/IF: Use at an assay dependent dilution (PMID 18083977).
IP: Use at an assay dependent dilution.
WB: 1/250 - 1/500. Predicted molecular weight: 49 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

Sequence similarities

Belongs to the cyclin family. Cyclin AB subfamily.

Developmental stage

Accumulates steadily during G2 and is abruptly destroyed at mitosis.

Cellular localization

Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER.

Target information above from: UniProt accessionP20248 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • CCN1 antibody
  • CCNA antibody
  • CCNA antibody
  • CCNA2 antibody
  • CCNA2_HUMAN antibody
  • Cyclin A2 antibody
  • Cyclin A2 antibody
  • Cyclin A2 antibody
  • Cyclin-A antibody
  • Cyclin-A2 antibody
see all

Database links

see all

References for Anti-Cyclin A antibody (ab2097)

This product has been referenced in:

  • Faustino RSet al. Ceramide regulation of nuclear protein import. J Lipid Res 49:654-62 (2008). ICC/IF; Rabbit.Read more (PubMed: 18083977) »
  • Rao HVet al. Cyclin D1, cdk4, and Bim are involved in thrombin-induced apoptosis in cultured cortical neurons. J Neurochem 101:498-505 (2007). WB; Rat.Read more (PubMed: 17254021) »

See all 2 publications for this product

Publishing research using ab2097? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"