Anti-Cyclin B1 antibody [V143.1] (ab18219)
- Product nameAnti-Cyclin B1 antibody [V143.1]See all Cyclin B1 primary antibodies ...
- DescriptionMouse monoclonal [V143.1] to Cyclin B1
- SpecificityExceptionally good at detecting cyclin B1 in western blots, giving a very strong signal with no background.
- Tested applicationsWB more details
- Species reactivityReacts with: Mouse
Full length protein (Hamster).
- EpitopeWithin a region spanning the carboxy region.
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
- Concentration information loading...
- PurityIgG fraction
- Clonality Monoclonal
- Clone numberV143.1
- Research Areas
Our Abpromise guarantee covers the use of ab18219 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use at an assay dependent dilution. Predicted molecular weight: 58 kDa.|
- FunctionEssential for the control of the cell cycle at the G2/M (mitosis) transition.
- Sequence similaritiesBelongs to the cyclin family. Cyclin AB subfamily.
- Developmental stageAccumulates steadily during G2 and is abruptly destroyed at mitosis.
modificationsUbiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.
- Cellular localizationCytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.
- CCNB 1 antibodyCCNB antibodyCCNB1 antibody
- CCNB1_HUMAN antibodyG2 mitotic specific cyclin B1 antibodyG2/mitotic-specific cyclin-B1 antibody
References for Anti-Cyclin B1 antibody [V143.1] (ab18219)
This product has been referenced in:
- Shen W et al. Female infertility in PDE3A (-/-) mice: Polo-like kinase 1 (Plk1) may be a target of Protein Kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A (-/- ) mice. Cell Cycle 9:4720-34 (2010). WB ; Mouse . Read more (PubMed: 21099356) »
- Geley S et al. Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. J Cell Biol 153:137-48 (2001). Read more (PubMed: 11285280) »