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Overview

  • Product nameAnti-Cyclin B1 antibodySee all Cyclin B1 primary antibodies ...
  • Description
    Rabbit polyclonal to Cyclin B1
  • Tested applicationsIHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Peptide from near the N terminal of Human Cyclin B1.

  • Positive controlBreast carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab93956 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
  • Application notesIHC-P: 1/50 - 1/500.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionEssential for the control of the cell cycle at the G2/M (mitosis) transition.
    • Sequence similaritiesBelongs to the cyclin family. Cyclin AB subfamily.
    • Developmental stageAccumulates steadily during G2 and is abruptly destroyed at mitosis.
    • Post-translational
      modifications      Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.
    • Cellular localizationCytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.

      • Target information above from: UniProt accession P14635 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          CCNB 1 antibodyCCNB antibodyCCNB1 antibody
          CCNB1_HUMAN antibodyG2 mitotic specific cyclin B1 antibodyG2/mitotic-specific cyclin-B1 antibody
        see all

      Anti-Cyclin B1 antibody images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cyclin B1 antibody (ab93956)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cyclin B1 antibody (ab93956)
        ab93956 at 1/100 dilution staining Cyclin B in formalin-fixed, paraffin-embedded Human breast carcinoma tissue. Note cytoplasmic and nuclear staining.

      References for Anti-Cyclin B1 antibody (ab93956)

      ab93956 has not yet been referenced specifically in any publications.

      Publishing research using ab93956 ? Please let us know so that we can cite the reference in this datasheet

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