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Products:Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cytochromes
Overview
Product name
Anti-Cytochrome P450 2B1 + 2B2 antibody [b/e4 (9.20)]
See all Cytochrome P450 2B1 + 2B2 products (2) ...
Description
Mouse monoclonal [b/e4 (9.20)] to Cytochrome P450 2B1 + 2B2
Specificity
Clone b/e4 does not react with CYP 1A1, 1A2, 2C6, 2C7, 2C11, 4A2, 4A3.
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Rat
Immunogen
Full length protein (Rat).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
b/e4 (9.20)
Isotype
IgG1
Research areas
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Metabolism
Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cytochromes
Applications
Show applications key
Our Abpromise guarantee covers the use of ab22721 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 56 kDa.
Target
Relevance
The Cytochrome P450 superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
Cellular localization
Membrane bound, endoplasmic reticulum
Alternative names
- Cyp2b 1 antibody
- Cyp2b 2 antibody
- Cyp2b1 antibody
see all
Database links
References for Anti-Cytochrome P450 2B1 + 2B2 antibody [b/e4 (9.20)] (ab22721)
ab22721 has not yet been referenced specifically in any publications.
Publishing research using ab22721? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"