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Cytochrome b5 protein (His tag) (ab56987)

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Overview

Product name

Cytochrome b5 protein (His tag)
See all Cytochrome b5 products (2) ...

Protein description

Recombinant Full length human Cytochrome b5 containing an N-terminal His tag.

Expression host

E. coli

Properties

Purity

> 90% by SDS-PAGE

Form

Liquid

Storage instructions

Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 20 mM phosphate buffer, 0.1mM EDTA, pH 7.25.

The product is supplied as a solution containing
0.5 - 10 mg protein (BCA)/mL

Concentration

Concentration information loading...

Research areas

Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Cytochromes
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Mitochondrial markers
Signal Transduction >> Metabolism >> Mitochondrial

Applications

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Our Abpromise guarantee covers the use of ab56987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Protein info

Function

Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.

Involvement in disease

Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]. A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia.

Sequence similarities

Belongs to the cytochrome b5 family.
Contains 1 cytochrome b5 heme-binding domain.

Cellular localization

Cytoplasm and Endoplasmic reticulum membrane. Microsome membrane.

Target information above from: UniProt accessionP00167 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for Cytochrome b5 protein (His tag) (ab56987)

ab56987 has not yet been referenced specifically in any publications.

Publishing research using ab56987? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"