Overview

  • Product nameAnti-Cytokeratin 13 antibody
    See all Cytokeratin 13 primary antibodies
  • Description
    Rabbit polyclonal to Cytokeratin 13
  • Tested applicationsWB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 198-448 of Human Cytokeratin 13 (NP_705694).

  • Positive control
    • WB: HeLa whole cell lysate ICC/IF: A431 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab97327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 50 kDa.
ICC/IF 1/100 - 1/200.

Target

  • Tissue specificityExpressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
  • Involvement in diseaseDefects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Post-translational
    modifications
    O-glycosylated; glycans consist of single N-acetylglucosamine residues.
  • Information by UniProt
  • Database links
  • Alternative names
    • 47 kDa cytokeratin antibody
    • CK-13 antibody
    • CK13 antibody
    • Cytokeratin 13 antibody
    • Cytokeratin-13 antibody
    • K13 antibody
    • K1C13_HUMAN antibody
    • Ka13 antibody
    • Keratin 13 antibody
    • Keratin antibody
    • keratin type I cytoskeletal 13 antibody
    • Keratin-13 antibody
    • Krt-1.13 antibody
    • Krt1-13 antibody
    • KRT13 antibody
    • MGC161462 antibody
    • MGC3781 antibody
    • type I cytoskeletal 13 antibody
    • Type I keratin Ka13 antibody
    see all

Anti-Cytokeratin 13 antibody images

  • Anti-Cytokeratin 13 antibody (ab97327) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 50 kDa
  • ab97327, at a 1/200 dilution, staining Cytokeratin 13 in paraformaldehyde fixed A431 cells by Immunofluorescence. Lower image is merged with DNA probe.

References for Anti-Cytokeratin 13 antibody (ab97327)

ab97327 has not yet been referenced specifically in any publications.

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