Anti-Cytokeratin 13 antibody (ab97327)

Overview

• Product nameAnti-Cytokeratin 13 antibodySee all Cytokeratin 13 primary antibodies ...
• Description
  Rabbit polyclonal to Cytokeratin 13
• Tested applicationsWB, ICC/IF more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse
• Immunogen

  Recombinant fragment corresponding to a region within amino acids 198-448 of Human Cytokeratin 13 (NP_705694).

• Positive controlWB: HeLa whole cell lysate ICC/IF: A431 cells

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Cytoskeleton / ECM
  • Cytoskeleton
  • Intermediate Filaments
  • Class I
  • Cytokeratins

  • Tags & Cell Markers
  • Cell Type Markers
  • Epi / Endo-thelial

Applications

Target

• Tissue specificityExpressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
• Involvement in diseaseDefects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
• Sequence similaritiesBelongs to the intermediate filament family.
• Post-translational
  modificationsO-glycosylated; glycans consist of single N-acetylglucosamine residues.

Target information above from: UniProt accession P13646 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3860 Human
  • Entrez Gene: 16663 Mouse
  • Omim: 148065 Human
  • SwissProt: P13646 Human
  • SwissProt: P08730 Mouse
  • Unigene: 654550 Human
  • Unigene: 4646 Mouse

• Alternative names
  47 kDa cytokeratin antibodyCK-13 antibodyCK13 antibody

  Cytokeratin 13 antibodyCytokeratin-13 antibodyK13 antibodyK1C13_HUMAN antibodyKa13 antibodyKeratin 13 antibodyKeratin antibodykeratin type I cytoskeletal 13 antibodyKeratin-13 antibodyKrt-1.13 antibodyKrt1-13 antibodyKRT13 antibodyMGC161462 antibodyMGC3781 antibodytype I cytoskeletal 13 antibodyType I keratin Ka13 antibody

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Anti-Cytokeratin 13 antibody images

• 

  Western blot - Cytokeratin 13 antibody (ab97327)
  Anti-Cytokeratin 13 antibody (ab97327) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
  
  Predicted band size : 50 kDa
  
• 

  Immunocytochemistry/ Immunofluorescence - Cytokeratin 13 antibody (ab97327)
  ab97327, at a 1/200 dilution, staining Cytokeratin 13 in paraformaldehyde fixed A431 cells by Immunofluorescence. Lower image is merged with DNA probe.