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Products:Tags & Cell Markers >> Subcellular Markers >> Organelles >> Peroxisome
Overview
Product name
Anti-D Amino Acid Oxidase antibody
See all D Amino Acid Oxidase products (6) ...
Description
Sheep polyclonal to D Amino Acid Oxidase
Specificity
Assay by immunoelectrophoresis resulted in a single precipitin arc against purified and partially purified D Amino Acid Oxidase.
Tested applications
Dot Blot, WB, ELISA, IP, Conjugationmore details
Cross reactivity
Reacts with
Pig
Immunogen
Full length D Amino Acid Oxidase protein (Pig Kidney).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.01% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate. pH 7.2
Concentration
Concentration information loading...
Purity
IgG fraction
Purification notes
This antibody was purified from monospecific antiserum by a multistep process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer.
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Metabolism >> Amino Acids
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Peroxisome
Applications
Show applications key
Our Abpromise guarantee covers the use of ab34697 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Dot Blot
WB
ELISA
IP
Conjugation
Application notes
Conjugation: Use at an assay dependent dilution.
Dot blot: Use at an assay dependent dilution.
ELISA: 1/20000 - 1/60000.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 39 kDa.
This antibody is also suitable for most immunological methods requiring high titer and specificity.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Sequence similarities
Belongs to the DAMOX/DASOX family.
Cellular localization
Peroxisome.
Target information above from: UniProt accessionP14920
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- D-amino-acid oxidase antibody
- DAAO antibody
- DAMOX antibody
see all
Database links
- Entrez Gene: 397134 Pig
- SwissProt: P00371 Pig
- Unigene: 232 Pig
References for Anti-D Amino Acid Oxidase antibody (ab34697)
ab34697 has not yet been referenced specifically in any publications.
Publishing research using ab34697? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"