Overview

  • Product name
    Anti-D-Dimer antibody [DD6] (HRP)
    See all D-Dimer primary antibodies
  • Description
    Mouse monoclonal [DD6] to D-Dimer (HRP)
  • Conjugation
    HRP
  • Specificity
    ab24474 is specific for D-dimer and high molecular weight fibrin degradation products. Low cross-reaction with D-monomer, cross-reaction with fibrinogen. Good for detection MAb in two-step sandwich IA.
  • Tested applications
    Suitable for: ELISA, WB, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    This clone has been derived from hybridization of Sp 2/0 myeloma cells with spleen cells of Balb/c mice immunized with homogenized fibrin clot.

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab24474 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 1 kDa.
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [DD1] to D-Dimer (ab10050). Can be used as Detection antibody. Recommended for D-Dimer detection in Human Plasma. Plasma must be diluted with 10 mM Tris/HCl buffer, pH 7.5, containing 1 M NaCl and 0.1 % Tween 20. To avoid non-specific binding, the final NaCl concentration in plasma samples must be 0.5 M or more. Less than 10 ng/ml of D-Dimer can be detected by DD1-DD6 assay using ordinary ELISA approach with HRP-labeled DD6 MAb

Target

  • Relevance
    A fibrin degradation fragment or product that is produced by the action of plasmin on fibrin in the clot dissolution process.
  • Alternative names
    • D Dimer antibody

References

This product has been referenced in:
  • Anderson N  et al. Protein biomarkers in exfoliated cells collected from the human rectal mucosa: implications for colorectal disease detection and monitoring. Int J Colorectal Dis 26:1287-97 (2011). ELISA ; Human . Read more (PubMed: 21698353) »

See 1 Publication for this product

Customer reviews and Q&As

Gracias por contactarnos.
Respecto a la especificidad de los anticuerpos anti-D-Dimer disponibles en el catálogo, los clones DD1, DD2 y DD3 son específicos para D Dimer y otros productos de pesos molecular elevados producto de la degradación de la...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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