Overview

  • Product name
    Anti-D Serine antibody
  • Description
    Rabbit polyclonal to D Serine
  • Host species
    Rabbit
  • Specificity
    Using conjugated D-Serine-Glutaraldehyde-Protein, antibody specificity was performed with an ELISA test by competition experiments with the following compounds: Compound : Cross-reactivity ratio(a) D-Serine-G-BSA: 1 L-Serine-G-BSA: 1/>50000 D-Cysteine-G-BSA: 1/>50000 D-Alanine-G-BSA: 1/>50000 (a) D-Serine-G-BSA concentration/unconjugated or conjugated amino acids concentration at half displacement G = Glutaraldehyde, BSA = Bovine Serum Albumin
  • Tested applications
    Suitable for: ELISA, IHC-Fr, IHC-FoFrmore details
  • Species reactivity
    Reacts with: Species independent
  • Immunogen

    Synthetic D-Serine conjugated to bovine serum albumin (BSA)

Properties

Applications

Our Abpromise guarantee covers the use of ab6472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000 - 1/25000.
IHC-Fr 1/12500.
IHC-FoFr Use at an assay dependent concentration. PubMed: 29194436

Target

  • Cellular localization
    Ubiquitous

Images

  • Ab6472 (1:2500) staining of cell bodies containing D Serine in the cerebral cortex of rat by immunohistochemistry.
  • Ab6472 (1:2500) staining of cell bodies containing D Serine in the cerebral cortex of rat by immunohistochemistry.

References

This product has been referenced in:
  • Kondori NR  et al. Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons. PLoS One 12:e0188912 (2017). IHC-FoFr ; Mouse . Read more (PubMed: 29194436) »
  • Perez EJ  et al. Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury. J Clin Invest 127:3114-3125 (2017). Read more (PubMed: 28714867) »

See all 6 Publications for this product

Customer reviews and Q&As

Thank you for your enquiry. Using conjugated D-Serine-Glutaraldehyde-Protein, antibody specificity was performed with an ELISA test by competition experiments with the following compounds: Compound : Cross-reactivity ratio(a) D-Serine-G-BSA: 1 L-S...

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Thank you for enquiry, sorry to hear you are experiencing problems, we will do our best to resolve them. Please could you confirm whether the results listed below refer to repeats in the same dilution, i.e have you obtained exactly the same results for...

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This antibody was raised against L-serine and only recognizes L-serine. We are in the process of raising antibodies against D-serine.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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