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- D4 GDI antibody (ab14230)
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Product Name
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D4 GDI antibody
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See all D4 GDI antibodies (8)...
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Product type
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Primary antibodies
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Description
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Chicken polyclonal to D4 GDI
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Immunogen
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Synthetic peptide: MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK TLLGDGPVVT , corresponding to amino acids 1-62 of Human D4 GDI.
BLAST 'MTEKAPEPHV EEDDDDELD S KLNYKPPP QK SLKELQE MDK DDESLI KYKK TLLGD ' with  or 
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Reacts with
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Hu, Ms, Rat, Cow
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: 1/500. Predicted molecular weight: 23 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic and Nuclear
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Research areas
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Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Other
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Assembly
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Relevance
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D4 GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Chicken
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Clonality
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Polyclonal
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Isotype
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IgY
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: PBS
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Form
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Liquid
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this D4 GDI antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for D4 GDI antibody images, references, products related to ab14230 and other tools.
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D4 GDI antibody images:
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 - D4 GDI antibody (ab14230)
Predicted band size : 23 kDa
Western blot with ab14230 at a dilution of 1/2000 against a D4 GDI fusion protein.
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Search PubMed (MEDLINE) for references to D4 GDI
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D4 GDI antibody - more information
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Customer reviews (feedback) regarding D4 GDI antibody |
Customer FAQs regarding D4 GDI antibody |
Protocols for D4 GDI antibody |
Price and availability of products related to D4 GDI antibody |
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D4 GDI antibody - related products:
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D4 GDI antibody - other tools:
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Contact Abcam with a Technical Enquiry about D4 GDI antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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