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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - D4 GDI antibody (ab88317)
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Western blot - D4 GDI antibody (ab88317)
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Product Name
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D4 GDI antibody
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See all D4 GDI antibodies (8)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to D4 GDI
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Immunogen
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Synthetic peptide from N terminal residues of Human D4 GDI protein.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: 1/50 - 1/200.
WB: 1/200 - 1/1000. Predicted molecular weight: 23 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Fetal tonsil tissue , jurkat and HL60 lysates
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Cellular localization
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Cytoplasmic and Nuclear
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Research areas
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Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Other
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Assembly
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Relevance
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D4 GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 2% BSA Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this D4 GDI antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for D4 GDI antibody images, references, products related to ab88317 and other tools.
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D4 GDI antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - D4 GDI antibody (ab88317)
Immunohistochemical staining of formalin-fixed paraffin-embedded fetal tonsil showing cytoplasmic and nuclear staining with ab88317 at a dilution of 1/100.
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Western blot - D4 GDI antibody (ab88317)
All lanes : D4 GDI antibody (ab88317) at 1/500 dilution
Lane 1 : Jurkat lysate
Lane 2 : HL60 lysate
Predicted band size : 23 kDa
Observed band size : 23 kDa
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Search PubMed (MEDLINE) for references to D4 GDI
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D4 GDI antibody - more information
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Customer reviews (feedback) regarding D4 GDI antibody |
Customer FAQs regarding D4 GDI antibody |
Protocols for D4 GDI antibody |
Price and availability of products related to D4 GDI antibody |
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D4 GDI antibody - related products:
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D4 GDI antibody - other tools:
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Contact Abcam with a Technical Enquiry about D4 GDI antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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