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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - D4 GDI antibody, prediluted (ab15199)
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Product Name
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D4 GDI antibody, prediluted
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See all D4 GDI antibodies (8)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to D4 GDI, prediluted
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Immunogen
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Recombinant full length protein (Human).
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: Use neat for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Placenta and tonsil.
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Cellular localization
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Cytoplasmic and Nuclear
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Research areas
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Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Other
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Assembly
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Relevance
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D4 GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Prediluted
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this D4 GDI antibody, prediluted is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for D4 GDI antibody, prediluted images, references, products related to ab15199 and other tools.
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D4 GDI antibody, prediluted images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - D4 GDI antibody, prediluted (ab15199)
ab15199 staining D4 GDI in human tonsil by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).
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Search PubMed (MEDLINE) for references to D4 GDI
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D4 GDI antibody, prediluted - more information
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