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Products:Stem Cells >> Signaling Pathways >> Wnt >> Cytoplasmic
Overview
Product name
Anti-DAAM2 antibody
Description
Rabbit polyclonal to DAAM2
Tested applications
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Synthetic peptide corresponding to a region between residues 150-200 of human DAAM2 (Q86T65).
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 0.05% BSA, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Stem Cells >> Signaling Pathways >> Wnt >> Cytoplasmic
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Western blot - DAAM2 antibody (ab72764)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab72764 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.5 - 1 µg/ml.Detects a band of approximately 100 kDa (predicted molecular weight: 124 kDa).
Target
Relevance
DAAM2, dishevelled associated activator of morphogenesis 2, belongs to the formin homology family and contains a DAD (diaphanous autoregulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/ formin homology 3) domain. It is a recently identified planar cell polarity (PCP) signaling molecule implicated in the regulation of cellular polarity, convergent extension, and invasion. It is suggested that DAAM2 is closely related to DAAM1 and hence along with DAAM1 it may also be required in Wnt/Fz signaling and activation of Rho and in regulating cytoskeleton architecture. It is expressed in most tissues examined.
Alternative names
- MGC90515 antibody
- dishevelled associated activator of morphogenesis 2 antibody
- dJ90A20A.1 antibody
see all
Database links
- Entrez Gene: 23500 Human
- Entrez Gene: 76441 Mouse
- Omim: 606627 Human
- SwissProt: Q86T65 Human
- SwissProt: Q80U19 Mouse
Anti-DAAM2 antibody images:
Western blot - DAAM2 antibody (ab72764)
All lanes : Anti-DAAM2 antibody (ab72764) at 0.5 µg/ml
Lane 1 : human skeletal muscle lysate
Lane 2 : human skeletal muscle lysate with immunizing peptide
Lane 3 : mouse skeletal muscle lysate
Predicted band size : 124 kDa
Observed band size : 100 kDa (why is the actual band size different from the predicted?)
References for Anti-DAAM2 antibody (ab72764)
ab72764 has not yet been referenced specifically in any publications.
Publishing research using ab72764? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"