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Anti-DAB2 antibody (ab20468)

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Overview

Product name

Anti-DAB2 antibody
See all DAB2 products (5) ...

Description

Goat polyclonal to DAB2

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide: C-SEMYRDPFGNPFA, corresponding to C terminal amino acids 758-770 of Human DAB2

C-SEMYRDPF GNPFA

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

HeLa lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris buffered saline. pH 7.3

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Tumor Suppressors
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Receptor Tyrosine Kinases

  • Western blot - DAB2 antibody (ab20468)Western blot - DAB2 antibody (ab20468) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab20468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 0.01 - 0.03 µg/ml.Detects a band of approximately 75 kDa (predicted molecular weight: 83 kDa).

Target

Relevance

DAB2 is a component of the CSF1 signal transduction pathway. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines. The down regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2 like domains, alpha and beta).

Cellular localization

Cytoplasmic vesicle; clathrin coated vesicle; clathrin coated vesicle membrane. Cell membrane; coated pit; clathrin coated pit. Note: Colocalizes with large insert containing isoforms of MYO6 at clathrin coated pits/vesicles.

Alternative names

  • DAB 2 antibody
  • Differentially expressed protein 2 antibody
  • disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) antibody
  • Disabled homolog 2 antibody
  • Disabled homolog 2 mitogen responsive phosphoprotein antibody
  • disabled homolog 2 mitogen-responsive phosphoprotein (Drosophila) antibody
  • DOC 2 antibody
  • DOC2 antibody
  • FLJ26626 antibody
  • Mitogen responsive phosphoprotein antibody
see all

Database links

Anti-DAB2 antibody images:

  Western blot - DAB2 antibody (ab20468)

Western blot - DAB2 antibody (ab20468)

Anti-DAB2 antibody (ab20468) at 0.003 µg/ml + Human Kidney lysate at 30 µg

Predicted band size : 83 kDa
Observed band size : 75 kDa (why is the actual band size different from the predicted?)

References for Anti-DAB2 antibody (ab20468)

ab20468 has not yet been referenced specifically in any publications.

Publishing research using ab20468? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"