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Western blot - DAB2 antibody (ab20468)
(enlarge)
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Product Name
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DAB2 antibody
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See all DAB2 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Goat polyclonal to DAB2
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Immunogen
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Synthetic peptide: C-SEMYRDPFGNPFA, corresponding to C terminal amino acids 758-770 of Human DAB2
BLAST 'C-SEMYRDPFGNPFA' with  or 
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 83 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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HeLa lysate
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Cellular localization
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Cytoplasmic vesicle; clathrin coated vesicle; clathrin coated vesicle membrane. Cell membrane; coated pit; clathrin coated pit.
Note: Colocalizes with large insert containing isoforms of MYO6 at clathrin coated pits/vesicles.
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Research areas
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Chromatin and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Tumor Suppressors
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Receptor Tyrosine Kinases
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Relevance
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DAB2 is a component of the CSF1 signal transduction pathway. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines. The down regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2 like domains, alpha and beta).
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris buffered saline. pH 7.3 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this DAB2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for DAB2 antibody images, references, products related to ab20468 and other tools.
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DAB2 antibody images:
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Search PubMed (MEDLINE) for references to DAB2
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DAB2 antibody - more information
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Customer reviews (feedback) regarding DAB2 antibody |
Customer FAQs regarding DAB2 antibody |
Protocols for DAB2 antibody |
Price and availability of products related to DAB2 antibody |
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DAB2 antibody - related products:
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DAB2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about DAB2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Western blot - DAB2 antibody (ab20468)