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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> Developmental Families >> Other
Overview
Product name
Anti-DACH2 antibody
See all DACH2 products (2) ...
Description
Rabbit polyclonal to DACH2
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Dog, Zebrafish
Immunogen
Synthetic peptide derived from a region between amino acids 525-574 of human DACH2. (Note:the exact amino acid sequence is proprietary)
Positive control
Jurkat cell lysate, human liver.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
-
Western blot - DACH2 antibody (ab30909)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab30909 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.5 µg/mlDetects a band of approximately 65 kDa.
Target
Relevance
DACH2 is a transcription factor that is involved in regulation of organogenesis. It seems to be a regulator for SIX1 and SIX6 and may act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. It probably binds to DNA via its DACH box-N domain.
Cellular localization
Nuclear
Alternative names
- DACH 2 antibody
- dachshund 2 antibody
- Dachshund homolog 2 (Drosophila) antibody
see all
Database links
- Entrez Gene: 612847 Dog
- Entrez Gene: 117154 Human
- Entrez Gene: 93837 Mouse
- Omim: 300608 Human
- SwissProt: Q96NX9 Human
- SwissProt: Q925Q8 Mouse
- Unigene: 86603 Human
Anti-DACH2 antibody images:
Western blot - DACH2 antibody (ab30909)
Anti-DACH2 antibody (ab30909) at 0.5 µg/ml + Jurkat cell lysate
Secondary
HRP conjugated anti-Rabbit IgG (1: 50,000 - 100,000)
Observed band size : 65 kDa (why is the actual band size different from the predicted?)
References for Anti-DACH2 antibody (ab30909)
ab30909 has not yet been referenced specifically in any publications.
Publishing research using ab30909? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"