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Anti-DAP Kinase 1 antibody [DAPK-55] (ab10443)

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Overview

Product name

Anti-DAP Kinase 1 antibody [DAPK-55]
See all DAP Kinase 1 products (4) ...

Description

Mouse monoclonal [DAPK-55] to DAP Kinase 1

Tested applications

WBmore details

Cross reactivity

Reacts with

Human, Monkey

Immunogen

Recombinant full length protein.

Positive control

COS-7 whole cell extract.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: Ascites

Concentration

Concentration information loading...

Purity

Ascites

Clonality

Monoclonal

Clone number

DAPK-55

Isotype

IgG1

Research areas

Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Cell Biology >> Apoptosis >> Intracellular >> Kinases
Cell Biology >> Apoptosis >> Extracellular Signals >> Death Ligands

Applications

Show applications key

Our Abpromise guarantee covers the use of ab10443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.

Sequence similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
Contains 10 ANK repeats.
Contains 1 death domain.
Contains 1 protein kinase domain.

Post-translational
modifications

Ubiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.

Cellular localization

Cytoplasm. Colocalizes with the actin filament system.

Target information above from: UniProt accessionP53355 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • DAK1 antibody
  • DAP K1 antibody
  • DAP kinase 1 antibody
  • DAPK 1 antibody
  • DAPK antibody
  • DAPK1 antibody
  • DAPK1_HUMAN antibody
  • Death Associated Protein Kinase 1 antibody
  • Death-associated protein kinase 1 antibody
  • DKFZp781I035 antibody
see all

Database links

References for Anti-DAP Kinase 1 antibody [DAPK-55] (ab10443)

This product has been referenced in:

  • Puto LA & Reed JC Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation. Genes Dev 22:998-1010 (2008).Read more (PubMed: 18413714) »

See 1 publication for this product

Publishing research using ab10443? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"