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Anti-DAP Kinase 1 (phospho S308) antibody [DKPS308] (ab10524)

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Overview

Product name

Anti-DAP Kinase 1 (phospho S308) antibody [DKPS308]
See all DAP Kinase 1 products (4) ...

Description

Mouse monoclonal [DKPS308] to DAP Kinase 1 (phospho S308)

Tested applications

ELISA, IP, Dot Blotmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide, corresponding to amino acids 303-312 (pSER308) of Human DAP Kinase 1.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: 0.01M PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Monoclonal

Clone number

DKPS308

Isotype

IgG1

Applications

Show applications key

Our Abpromise guarantee covers the use of ab10524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     
  • IP

     
  • Dot Blot

     

Application notes

Dot: Use at a concentration of 1 - 2 µg/ml, Determined by immunoblotting using 293T (human embryonal kidney) cells transfected with DAPKinase expression vector.
ELISA: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.

Sequence similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
Contains 10 ANK repeats.
Contains 1 death domain.
Contains 1 protein kinase domain.

Post-translational
modifications

Ubiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.

Cellular localization

Cytoplasm. Colocalizes with the actin filament system.

Target information above from: UniProt accessionP53355 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • DAK1 antibody
  • DAP K1 antibody
  • DAP kinase 1 antibody
  • DAPK 1 antibody
  • DAPK antibody
  • DAPK1 antibody
  • DAPK1_HUMAN antibody
  • Death Associated Protein Kinase 1 antibody
  • Death-associated protein kinase 1 antibody
  • DKFZp781I035 antibody
see all

References for Anti-DAP Kinase 1 (phospho S308) antibody [DKPS308] (ab10524)

ab10524 has not yet been referenced specifically in any publications.

Publishing research using ab10524? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"