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Anti-DAP Kinase 1 (phospho S308) antibody [DKPS308] (ab10524)

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Overview

Product name

Anti-DAP Kinase 1 (phospho S308) antibody [DKPS308]
See all DAP Kinase 1 products (4) ...

Description

Mouse monoclonal [DKPS308] to DAP Kinase 1 (phospho S308)

Tested applications

ELISA, IP, Dot Blotmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide, corresponding to amino acids 303-312 (pSER308) of Human DAP Kinase 1.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: 0.01M PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Monoclonal

Clone number

DKPS308

Isotype

IgG1

Research areas

Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Cell Biology >> Apoptosis >> Intracellular >> Kinases
Cell Biology >> Apoptosis >> Extracellular Signals >> Death Ligands

Applications

Show applications key

Our Abpromise guarantee covers the use of ab10524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     

  • IP

     

  • Dot Blot

     

Application notes

Dot: Use at a concentration of 1 - 2 µg/ml, Determined by immunoblotting using 293T (human embryonal kidney) cells transfected with DAPKinase expression vector.
ELISA: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.

Sequence similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
Contains 10 ANK repeats.
Contains 1 death domain.
Contains 1 protein kinase domain.

Post-translational
modifications

Ubiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.

Cellular localization

Cytoplasm. Colocalizes with the actin filament system.

Target information above from: UniProt accessionP53355 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • DAK1 antibody
  • DAP K1 antibody
  • DAP kinase 1 antibody
  • DAPK 1 antibody
  • DAPK antibody
  • DAPK1 antibody
  • DAPK1_HUMAN antibody
  • Death Associated Protein Kinase 1 antibody
  • Death-associated protein kinase 1 antibody
  • DKFZp781I035 antibody
see all

Database links

References for Anti-DAP Kinase 1 (phospho S308) antibody [DKPS308] (ab10524)

ab10524 has not yet been referenced specifically in any publications.

Publishing research using ab10524? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"