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Products:Cell Biology >> Apoptosis >> Intracellular >> Kinases
Overview
Product name
Anti-DAP Kinase 2 (phospho S318) antibody
See all DAP Kinase 2 products (12) ...
Description
Rabbit polyclonal to DAP Kinase 2 (phospho S318)
Specificity
Detects endogenous levels of DAP Kinase 2 only when phosphorylated at serine 318.
Tested applications
ELISA, IHC-Pmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Synthetic phosphopeptide derived from human DAP Kinase 2 around the phosphorylation site of serine 318 (K-L-SP-F-S).
Positive control
Skeletal muscle
Properties
Form
Liquid
Storage instructions
Store at -20°C. Stable for 12 months at -20°C
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
Affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Clonality
Polyclonal
Isotype
IgG
Research areas
Cell Biology >> Apoptosis >> Intracellular >> Kinases
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DAP Kinase 2 (phospho S318) antibody (ab61042)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab61042 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/5000ELISA: 1/5000
IHC-P: 1/50 - 1/100.
Target
Function
Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
Tissue specificity
Ubiquitously expressed in all tissue types examined. High levels in heart, lung and skeletal muscle.
Sequence similarities
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
Contains 1 protein kinase domain.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionQ9UIK4
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- DAK 2 antibody
- DAK2 antibody
- DAP kinase 2 antibody
see all
Database links
- Entrez Gene: 23604 Human
- Entrez Gene: 13143 Mouse
- Omim: 604727 Human
- SwissProt: Q9UIK4 Human
- SwissProt: Q8VDF3 Mouse
- Unigene: 237886 Human
- Unigene: 304472 Mouse
- Unigene: 335252 Mouse
Anti-DAP Kinase 2 (phospho S318) antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DAP Kinase 2 (phospho S318) antibody (ab61042)
1/50-1/100 ab61042 staining phosphorilated DAP Kinase 2 in human skeletal muscle tissue, in the absence or presence of the immunizing phosphopeptide.
References for Anti-DAP Kinase 2 (phospho S318) antibody (ab61042)
ab61042 has not yet been referenced specifically in any publications.
Publishing research using ab61042? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"