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Overview

  • Product nameDAP Kinase 2 protein (Active)See all DAP Kinase 2 proteins and peptides ...
  • Protein descriptionRecombinant full length Human DAP Kinase 2 with an N-terminal terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-370, 67kDa. UniProt = Q9UIK4.
  • Expression hostBaculovirus infected sf9 cells

    • Properties

  • Purification notesPurity was determined to be >80% by densitometry.
  • Biological activityThe Specific activity of ab89742 was determined to be 136 nmol/min/mg.
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferPreservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab89742 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent dilution. Predicted molecular weight: 43 kDa.
    Functional Studies FuncS: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        DAK2DAP kinase 2DAP kinase related protein 1
        DAP kinase related protein 1 beta isoformDAP-kinase-related protein 1DAPK2DAPK2_HUMANDeath associated protein kinase 2Death-associated protein kinase 2DRP 1DRP-1DRP1MGC119312
      see all
  • FunctionCalcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
  • Tissue specificityUbiquitously expressed in all tissue types examined. High levels in heart, lung and skeletal muscle.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationCytoplasm.

    • Target information above from: UniProt accession Q9UIK4 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    DAP Kinase 2 protein (Active) images

    • SDS-PAGE - DAP Kinase 2 protein (Active) (ab89742)
      SDS-PAGE - DAP Kinase 2 protein (Active) (ab89742)
      SDS-PAGE showing ab89742 at approximately 67kDa.
    • Functional Studies - DAP Kinase 2 protein (Active) (ab89742)
      Functional Studies - DAP Kinase 2 protein (Active) (ab89742)
      Kinase Assay demonstrating specific activity of ab89742.

    References for DAP Kinase 2 protein (Active) (ab89742)

    ab89742 has not yet been referenced specifically in any publications.

    Publishing research using ab89742 ? Please let us know so that we can cite the reference in this datasheet

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