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Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab54972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionAppears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
    • Tissue specificityUbiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.
    • Sequence similaritiesBelongs to the eIF4G family.
      Contains 1 MI domain.
      Contains 1 MIF4G domain.
      Contains 1 W2 domain.
    • Post-translational
      modifications      Phosphorylation; hyperphosphorylated during mitosis.

      • Target information above from: UniProt accession P78344 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          DAP-5 antibodyDeath associated protein 5 antibodyDeath-associated protein 5 antibody
          eIF-4-gamma 2 antibodyeIF-4G 2 antibodyeIF4G 2 antibodyEIF4G2 antibodyEukaryotic translation initiation factor 4 gamma 2 antibodyIF4G2_HUMAN antibodyNat1 antibodyNovel APOBEC-1 target 1 antibodyp97 antibodyTranslation repressor NAT1 antibody
        see all

      Anti-DAP5 antibody images

      • IHC-P - DAP5 antibody (ab54972)
        IHC-P - DAP5 antibody (ab54972)
        DAP5 antibody (ab54972) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human heart.
      • Western blot - DAP5 antibody (ab54972)
        Western blot - DAP5 antibody (ab54972)


        Predicted band size : 102 kDa
        DAP5 antibody (ab54972) at 1ug/lane + HeLa cell lysate at 25ug/lane.

      References for Anti-DAP5 antibody (ab54972)

      ab54972 has not yet been referenced specifically in any publications.

      Publishing research using ab54972 ? Please let us know so that we can cite the reference in this datasheet

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