Anti-DAP5 antibody (ab69635)

Overview

• Product nameAnti-DAP5 antibodySee all DAP5 primary antibodies ...
• Description
  Rabbit polyclonal to DAP5
• Tested applicationsWB, ELISA more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse
• Immunogen

  synthesized peptide derived from internal of human DAP5

• Positive controlExtracts from A549 cells.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 50% Glycerol, PBS (without Mg²⁺ and Ca²⁺), 150mM Sodium chloride, pH 7.4
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • Translation
  • Regulation

  • Cell Biology
  • Apoptosis
  • Nucleus
  • Other

  • Cell Biology
  • Apoptosis
  • Receptors
  • Death Receptors

Applications

Target

• FunctionAppears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
• Tissue specificityUbiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.
• Sequence similaritiesBelongs to the eIF4G family.
  Contains 1 MI domain.
  Contains 1 MIF4G domain.
  Contains 1 W2 domain.
• Post-translational
  modificationsPhosphorylation; hyperphosphorylated during mitosis.

Target information above from: UniProt accession P78344 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 1982 Human
  • Entrez Gene: 1982 Human
  • Entrez Gene: 13690 Mouse
  • Omim: 602325 Human
  • SwissProt: P78344 Human
  • SwissProt: P78344 Human
  • SwissProt: Q62448 Mouse
  • Unigene: 183684 Human

  • Unigene: 185453 Mouse

  see all

• Alternative names
  DAP-5 antibodyDeath associated protein 5 antibodyDeath-associated protein 5 antibody

  eIF-4-gamma 2 antibodyeIF-4G 2 antibodyeIF4G 2 antibodyEIF4G2 antibodyEukaryotic translation initiation factor 4 gamma 2 antibodyIF4G2_HUMAN antibodyNat1 antibodyNovel APOBEC-1 target 1 antibodyp97 antibodyTranslation repressor NAT1 antibody

  see all

Anti-DAP5 antibody images

• 

  Western blot - DAP5 antibody (ab69635)
  All lanes : Anti-DAP5 antibody (ab69635) at 1/500 dilution
  
  Lane 1 : Extracts from A549 cells
  Lane 2 : Extracts from A549 cells with immunising peptide at 5 µg
  
  Lysates/proteins at 5 µg per lane.
  
  
  Predicted band size : 102 kDa
  Observed band size : 102 kDa
  Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.