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Products:Immunology >> Adaptive Immunity >> B Cells >> Non-CD
Overview
Product name
Anti-DAPP1 antibody
See all DAPP1 products (5) ...
Description
Chicken polyclonal to DAPP1
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
This information is considered to be commercially sensitive
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgY
Research areas
Signal Transduction >> Adapters >> Cytoplasmic
Immunology >> Adaptive Immunity >> B Cells >> Non-CD
Applications
Show applications key
Our Abpromise guarantee covers the use of ab49926 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/2000Predicted molecular weight: 32 kDa.
Target
Function
May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
Tissue specificity
Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
Sequence similarities
Contains 1 PH domain.
Contains 1 SH2 domain.
Post-translational
modifications
Phosphorylated on tyrosine residues.
Cellular localization
Cytoplasm. Membrane. Membrane-associated after cell stimulation leading to its translocation.
Target information above from: UniProt accessionQ9UN19
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- DKFZp667E0716 antibody
- B cell adapter molecule of 32 kDa antibody
- B lymphocyte adapter protein Bam32 antibody
see all
Database links
- Entrez Gene: 27071 Human
- NCBI: 7657007 Human
- Omim: 605768 Human
- SwissProt: Q9UN19 Human
- Unigene: 436271 Human
- Unigene: 708484 Human
References for Anti-DAPP1 antibody (ab49926)
ab49926 has not yet been referenced specifically in any publications.
Publishing research using ab49926? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"