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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Overview
Product name
DAZL peptide (240-250) (Carboxyterminal end)
See all DAZL products (3) ...
Protein description
Synthetic peptide: C-GNGPQKKSVDR, corresponding to internal sequence amino acids 240-250 of Human DAZL This peptide was used as an immunogen for ab40848 - DAZL antibody.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration
Concentration information loading...
Sequence
C-GNGPQKKS VDR
Research areas
Developmental Biology >> Reproduction >> Germ cell markers
Stem Cells >> Germline Stem Cells >> Embryonic Germ Cells
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Protein info
Function
RNA-binding protein, which is essential for gametogenesis. Plays a central role during spermatogenesis. May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts.
Tissue specificity
Testis specific.
Sequence similarities
Belongs to the RRM DAZ family.
Contains 1 DAZ-like domain.
Contains 1 RRM (RNA recognition motif) domain.
Domain
The DAZ-like domain mediates the interaction with DAZAP1 and DAZAP2.
Cellular localization
Cytoplasm. Nucleus. Predominantly cytoplasmic (By similarity). Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.
Target information above from: UniProt accessionQ92904
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for DAZL peptide (240-250) (Carboxyterminal end) (ab45790)
ab45790 has not yet been referenced specifically in any publications.
Publishing research using ab45790? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"