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AbcamBiochemicals (Asc-708)

[D-Ala2]-Deltorphin II (ab120708)

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Overview

  • Product name[D-Ala2]-Deltorphin II
  • Description
    Selective δ opioid receptor agonist
  • Biological descriptionSelective δ opioid receptor agonist (Ki values are 1.5, >1,000 and >1,000 nM for opioid receptor subtypes δ, μ and κ respectively). Anti-nociceptive activity. Centrally active following intravenous administration.
  • Purity> 98%

    • Properties

  • Chemical nameYAFEVVG-NH2 (Modifications: Ala-2 = D-Ala)
  • Molecular Weight782.89
  • Chemical structureChemical Structure
  • Molecular formulaC38H54N8O10
  • CAS Number122752-16-3
  • Storage instructionsStore at -20°C (desiccating conditions).
  • Solubility overviewSoluble in water to 0.5 mg/ml
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • Source

    Synthetic

  • Research Areas

    • References for [D-Ala2]-Deltorphin II (ab120708)

    This product has been referenced in:
    • Labuz D  et al. Endomorphin-2, deltorphin II and their analogs suppress formalin-induced nociception and c-Fos expression in the rat spinal cord. Life Sci 73:403-12 (2003). Read more (PubMed: 12759135) »
    • Toll L  et al. Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr 178:440-66 (1998). Read more (PubMed: 9686407) »
    • Fiori A  et al. Deltorphin transport across the blood-brain barrier. Proc Natl Acad Sci U S A 94:9469-74 (1997). Read more (PubMed: 9256506) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"