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Products:Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> Tubulin
Overview
Product name
DCDC2 peptide (352-365)
Protein description
Synthetic peptide: C-DGEKANKDA EQKED, corresponding to internal sequence amino acids 352-365 of Human DCDC2. This peptide was used as an immunogen for ab45868 - DCDC2 antibody. Note: The Valine is left out in favor of a Cysteine residue for conjugation purposes.
Properties
Form
Liquid
Storage instructions
Store at -20°C. Stable for 12 months at -20°C
Concentration
Concentration information loading...
Sequence
C-DGEKANKD A EQKED
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Sensory System >> Visual system
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> Tubulin
Protein info
Function
May be involved in neuronal migration during development of the cerebral neocortex.
Tissue specificity
Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus.
Involvement in disease
Defects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability.
Sequence similarities
Contains 2 doublecortin domains.
Target information above from: UniProt accessionQ9UHG0
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for DCDC2 peptide (352-365) (ab45880)
ab45880 has not yet been referenced specifically in any publications.
Publishing research using ab45880? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"