You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameDCDC2 protein (His-DHFR tag)See all DCDC2 proteins and peptides ...
  • Protein descriptionRecombinant fragment corresponding to amino acids 7-212 of Human DCDC2 with N terminal His-DHFR tag; Predicted MWt 23.2 kDa excluding tag (BC050704).
  • Uniprot accessionQ9UHG0
  • Molecular weight23.200kDa
  • Protein length206 amino acids
  • Expression hostE. coli

    • Properties

  • Purification notesPurity determined to be >95% by SDS-PAGE.
  • FormLyophilised:Reconstitute with water to desired concentration
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab127294 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        DCDC 2DCDC2DCDC2_HUMAN
        DCDC2ADoublecortin domain containing 2doublecortin domain containing protein 2Doublecortin domain-containing protein 2HGNC:18141KIAA1154Protein RU2SRU 2RU2RU2SRU2S protein
      see all
  • FunctionMay be involved in neuronal migration during development of the cerebral neocortex.
  • Tissue specificityUbiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus.
  • Involvement in diseaseDefects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability.
  • Sequence similaritiesContains 2 doublecortin domains.

    • Target information above from: UniProt accession Q9UHG0 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for DCDC2 protein (His-DHFR tag) (ab127294)

    ab127294 has not yet been referenced specifically in any publications.

    Publishing research using ab127294 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab127294 Submit a Question for ab127294

    There are currently no Abreviews or Questions for ab127294.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"