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Overview

  • Product nameDCPS protein
  • Protein descriptionRecombinant full-length Human DCPS (amino acids 1-337) with a N terminal His tag. 357 amino acids with a predicted MWt 40.8 kDa including tag . NCBI Accession No.: NP_054745.
  • Uniprot accessionQ96C86
  • Molecular weight40.800kDa inclusive of tags
  • Protein length337 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 90 % by SDS-PAGE
  • Purification notesab113138 was purified using conventional chromatography.
  • Mass spectrometryMALDI-TOF
  • E.C. Number3.-.-.-
  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
    Mix suspension via gentle inversion before use.
  • Storage bufferpH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT
  • Concentration information loading...
  • Sequence notesMGSSHHHHHHSSGLVPRGSHMADAAPQLGKRKRELDV EEAHAASTEEKEAGVGNGTCAPVRLPFSGFR LQKVLRE SARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVA QLLTGSPELQLQFSNDIYSTYHLFPPRQ LNDVKTTVVY PATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSI QWVYNILDKKAEADRIVFENPDPSD GFVLIPDLKWNQQ QLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEA ILQRYRMKGDHLRVYLHYLPSY YHLHVHFTALGFEAPG SGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLK LLQEAQQS
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab113138 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    Functional Studies FuncS: Use at an assay dependent concentration.
  • Application notesThis peptide can be used with studies using ab139350 and ab154006.

    • Protein info

    • Alternative names
        1700001E16RikAA408441DCPS
        DCPS_HUMANDCS 1DCS-1DCS1Decapping enzyme scavengerheat shock-like protein 1Hint 5Hint related 7meGMP directed hydrolaseHINT-5Hint-related 7meGMP-directed hydrolaseHINT5Histidine triad protein member 5homolog of C. elegans 7meGMP-directed hydrolase dcs-1HSL1HSPC015m7GpppX diphosphataseMGC124934mRNA decapping enzymeOTTMUSP00000042220Scavenger mRNA decapping enzyme DcpSScavenger mRNA-decapping enzyme DcpS
      see all
  • FunctionNecessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
  • Tissue specificityDetected in liver, brain, kidney, testis and prostate.
  • Sequence similaritiesBelongs to the HIT family.
  • Cellular localizationCytoplasm. Nucleus.

    • Target information above from: UniProt accession Q96C86 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    DCPS protein images

    • SDS-PAGE - DCPS protein (ab113138)
      SDS-PAGE - DCPS protein (ab113138)
      15% SDS-PAGE analysis of (3µg)

    References for DCPS protein (ab113138)

    ab113138 has not yet been referenced specifically in any publications.

    Publishing research using ab113138 ? Please let us know so that we can cite the reference in this datasheet

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