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Products:Cell Biology >> Apoptosis >> Nucleus >> DNAses
Overview
Product name
Anti-DFFB antibody
See all DFFB products (12) ...
Description
Rabbit polyclonal to DFFB
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Mouse
Immunogen
Synthetic peptide, corresponding to C terminal amino acids 314-329 of Mouse DFFB(Peptide available as ab8432.)
Positive control
Tissue lysate from murine lung or kidney. A 40 kDa band should be detected.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
PBS with 0.02% sodium azide
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Polyclonal
Isotype
IgG
Light chain type
unknown
Research areas
Epigenetics and Nuclear Signaling >> Cell cycle >> Apoptosis >> Nuclear
Cell Biology >> Apoptosis >> Nucleus >> Chromatin Condensation
Cell Biology >> Apoptosis >> Nucleus >> DNAses
Applications
Show applications key
Our Abpromise guarantee covers the use of ab8400 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Predicted molecular weight: 39 kDa.
IHC-P: Use a concentration of 1 µg/ml
Target
Relevance
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. The DNA fragmentation factor (DFF) described by Liu et al. (1997) is a heterodimer of 40 kD (DFFB) and 45 kD (DFFA; 601882) subunits.
Cellular localization
Cytoplasmic and Nuclear
Alternative names
- CAD antibody
- Caldesmon antibody
- Caspase activated deoxyribonuclease antibody
see all
Database links
- Entrez Gene: 13368 Mouse
- SwissProt: O54788 Mouse
Anti-DFFB antibody images:
Western blot - CAD antibody (ab8400)
All lanes : Anti-DFFB antibody (ab8400) at 1/500 dilution
Lane 1 : Murine lung tissue lysate
Lane 2 : Murine kidney tissue lysate
Predicted band size : 39 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CAD antibody (ab8400)
ab8400 at 1µg/ml staining CAD in mouse kidney tissue by IHC
References for Anti-DFFB antibody (ab8400)
ab8400 has not yet been referenced specifically in any publications.
Publishing research using ab8400? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"