Overview

  • Product nameAnti-DLL4 antibody
    See all DLL4 primary antibodies
  • Description
    Rabbit polyclonal to DLL4
  • Tested applicationsWB, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 27-524 of Human DLL4

  • General notesThe lyophilized antibody is stable for at least 2 years from date of receipt at -20oC. The reconstituted antibody is stable for at least two weeks at 2-8oC. Frozen aliquots are stable for at least 6 months when stored at -20oC. Avoid repeated freeze-thaw cycles.

Properties

Applications

Our Abpromise guarantee covers the use of ab107518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 75 kDa.
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml.

Target

  • FunctionPlays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.
  • Tissue specificityExpressed in vascular endothelium.
  • Sequence similaritiesContains 1 DSL domain.
    Contains 8 EGF-like domains.
  • DomainThe Delta-Serrate-Lag2 (DSL) domain is required for binding to the Notch receptor.
  • Post-translational
    modifications
    Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Delta 4 antibody
    • delta 4 precursor antibody
    • Delta ligand 4 antibody
    • delta ligand 4 precursor antibody
    • Delta like 4 antibody
    • Delta like 4 homolog antibody
    • Delta like 4 protein antibody
    • Delta like protein 4 antibody
    • Delta-like 4 (Drosophila) antibody
    • Delta-like protein 4 antibody
    • Delta4 antibody
    • DLL 4 antibody
    • Dll4 antibody
    • DLL4_HUMAN antibody
    • Drosophila Delta homolog 4 antibody
    • hdelta2 antibody
    • Homeobox protein DLL-4 antibody
    • MGC126344 antibody
    • Notch ligand delta 2 antibody
    • Notch ligand DLL4 antibody
    • Notch ligand DLL4 precursor antibody
    • XDLL-4 antibody
    see all

References for Anti-DLL4 antibody (ab107518)

ab107518 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"