Overview
- Product nameAnti-DLL4 antibodySee all DLL4 primary antibodies ...
- DescriptionRabbit polyclonal to DLL4
- Tested applicationsWB, Sandwich ELISA more details
- Species reactivityReacts with: Recombinant Fragment
Predicted to work with: Human - Immunogen
Recombinant full length protein, corresponding to amino acids 27-524 of Human DLL4
- General notesThe lyophilized antibody is stable for at least 2 years from date of receipt at -20oC. The reconstituted antibody is stable for at least two weeks at 2-8oC. Frozen aliquots are stable for at least 6 months when stored at -20oC. Avoid repeated freeze-thaw cycles.
Properties
- FormLyophilised
- Storage instructionsShipped at 4°C. Store at -20ºC.
- Storage bufferPreservative: None
Constituents: PBS, pH 7.2 -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab107518 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 75 kDa. |
| Sandwich ELISA | sELISA: Use a concentration of 0.5 - 2 µg/ml. |
Target
- FunctionPlays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.
- Tissue specificityExpressed in vascular endothelium.
- Sequence similaritiesContains 1 DSL domain.
Contains 8 EGF-like domains. - DomainThe Delta-Serrate-Lag2 (DSL) domain is required for binding to the Notch receptor.
- Post-translational
modificationsUbiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. - Cellular localizationMembrane.
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Database links
- Entrez Gene: 54567 Human
- Entrez Gene: 54567 Human
- Omim: 605185 Human
- SwissProt: Q9NR61 Human
- SwissProt: Q9NR61 Human
- Unigene: 511076 Human
Target information above from: UniProt accession
Q9NR61
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Delta 4 antibodydelta 4 precursor antibodyDelta ligand 4 antibody
- delta ligand 4 precursor antibodyDelta like 4 antibodyDelta like 4 homolog antibodyDelta like 4 protein antibodyDelta like protein 4 antibodyDelta-like 4 (Drosophila) antibodyDelta-like protein 4 antibodyDelta4 antibodyDLL 4 antibodyDll4 antibodyDLL4_HUMAN antibodyDrosophila Delta homolog 4 antibodyhdelta2 antibodyHomeobox protein DLL-4 antibodyMGC126344 antibodyNotch ligand delta 2 antibodyNotch ligand DLL4 antibodyNotch ligand DLL4 precursor antibodyXDLL-4 antibody
see all
References for Anti-DLL4 antibody (ab107518)
ab107518 has not yet been referenced specifically in any publications.
