Anti-DLST antibody (ab95946)

Overview

• Product nameAnti-DLST antibodySee all DLST primary antibodies ...
• Description
  Rabbit polyclonal to DLST
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Cow, Pig, Zebrafish
• Immunogen

  Recombinant protein fragment containing a sequence corresponding to a region within amino acids 188-423 of Human DLST

• Positive controlA431 whole cell lysate

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Amino acid metabolism

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Signal Transduction
  • Metabolism
  • Mitochondrial

  • Signal Transduction
  • Metabolism
  • Amino Acids

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

Applications

Target

• FunctionThe 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
• PathwayAmino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.
• Sequence similaritiesBelongs to the 2-oxoacid dehydrogenase family.
  Contains 1 lipoyl-binding domain.
• Cellular localizationMitochondrion.

Target information above from: UniProt accession P36957 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 1743 Human
  • Entrez Gene: 78920 Mouse
  • Entrez Gene: 299201 Rat
  • Omim: 126063 Human
  • SwissProt: P36957 Human
  • SwissProt: Q9D2G2 Mouse
  • SwissProt: Q01205 Rat
  • Unigene: 525459 Human

  • Unigene: 296221 Mouse
  • Unigene: 99702 Rat

  see all

• Alternative names
  2-oxoglutarate dehydrogenase complex component E2 antibodyDihydrolipoamide S succinyltransferase (E2 component of 2 oxo glutarate complex) antibodyDihydrolipoamide S succinyltransferase antibody

  Dihydrolipoamide succinyltransferase component of 2 oxoglutarate dehydrogenase complex antibodyDihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex antibodyDihydrolipoyllysine residue succinyltransferase component of 2 oxoglutarate dehydrogenase complex antibodyDihydrolipoyllysine residue succinyltransferase component of 2 oxoglutarate dehydrogenase complex mitochondrial antibodyDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex antibodyDlst antibodyDLTS antibodyE2 antibodyE2K antibodymitochondrial antibodyODO2_HUMAN antibodyOGDC-E2 antibody

  see all

Anti-DLST antibody images

• 

  Western blot - DLST antibody (ab95946)
  Anti-DLST antibody (ab95946) at 1/1000 dilution + A431 whole cell lysate at 30 µg
  
  Predicted band size : 49 kDa