DNA Polymerase delta, catalytic subunit antibody [607] (ab10362)

Product Name 

DNA Polymerase delta, catalytic subunit antibody [607]

Product type 

Primary antibodies

Description 

Mouse monoclonal [607] to DNA Polymerase delta, catalytic subunit

Immunogen 

Recombinant protein, corresponding to amino acids 1-140 of the large subunit of Human DNA Polymerase delta.

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB

Abreviews 

Customer reviews (see key)

Read about Abreviews (Read all Abreviews)

Application notes 
(see key)

Recommended dilutions
WB: 1/1000. Detects a band of approximately 130 kDa (predicted molecular weight: 130 kDa).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

HeLa whole cell lysate.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Synthesis >> DNA Polymerases

Relevance 

The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA), the multisubunit replication factor C, and the 4 subunit polymerase complex: DNA Polymerase delta, catalytic subunit (POLD1), POLD2, POLD3, and POLD4.

Database links 

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

607

Myeloma 

NS1

Isotype 

IgG

Purity 

Protein G purified

Storage buffer 

Preservative: None
Constituents: PBS

Purification notes 

Antibody purified from hybridoma cell culture supernatant by protein G chromatography to at least 95% homogeneity as determined by SDS-PAGE.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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References for DNA Polymerase delta, catalytic subunit antibody [607] (ab10362)

  This product has been used in: (two most recent references)

Akbari M et al. Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity. DNA Repair (Amst) 8:834-43 (2009). WB; Human. PubMed: 19442590

Yoo MH et al. Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication. PLoS ONE 2:e1112 (2007). WB. PubMed: 17971875

See all 3 publication references for this product.


If you publish research using ab10362 please let us know so that we can cite the reference on this datasheet.

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