Anti-DOCK9/Trg antibody (ab70272)
Key features and details
- Rabbit polyclonal to DOCK9/Trg
- Suitable for: WB, IP
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DOCK9/Trg antibody
See all DOCK9/Trg primary antibodies -
Description
Rabbit polyclonal to DOCK9/Trg -
Host species
Rabbit -
Tested applications
Suitable for: WB, IPmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Opossum, Orangutan -
Immunogen
Synthetic peptide, corresponding to amino acids 1-50 of Human DOCK9 (NP_056111.1)
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Positive control
- HeLa whole cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab70272 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/5000 - 1/15000. Detects a band of approximately 236 kDa (predicted molecular weight: 236 kDa).
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IP |
Use at 2-5 µg/mg of lysate.
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Notes |
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WB
1/5000 - 1/15000. Detects a band of approximately 236 kDa (predicted molecular weight: 236 kDa). |
IP
Use at 2-5 µg/mg of lysate. |
Target
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Function
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation. -
Tissue specificity
Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle. -
Sequence similarities
Belongs to the DOCK family.
Contains 1 DHR-1 domain.
Contains 1 DHR-2 domain.
Contains 1 PH domain. -
Domain
The DHR-2 domain is necessary and sufficient for the GEF activity. -
Cellular localization
Endomembrane system. Associated with membranes. - Information by UniProt
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Database links
- Entrez Gene: 23348 Human
- Omim: 607325 Human
- SwissProt: Q9BZ29 Human
- Unigene: 596105 Human
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Alternative names
- Cdc42 guanine nucleotide exchange factor zizimin 1 antibody
- Cdc42 guanine nucleotide exchange factor zizimin-1 antibody
- Dedicator of cytokinesis protein 9 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab70272 has been referenced in 1 publication.
- Wieczfinska J et al. The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir Res 16:147 (2015). WB . PubMed: 26646719