You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-DOPA Decarboxylase antibody (ab32587)

Submit an Abreview Q&A (1)

Overview

  • Product nameAnti-DOPA Decarboxylase antibodySee all DOPA Decarboxylase primary antibodies ...
  • Description
    Rabbit polyclonal to DOPA Decarboxylase
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Rat, Sheep, Rabbit, Guinea pig, Cow, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to amino acids from the N terminus of DOPA Decarboxylase (Human) conjugated to KLH.

  • Positive controlBovine adrenal medulla lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab32587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/1000. Detects a band of approximately 55 kDa (predicted molecular weight: 54 kDa).

Target

  • FunctionCatalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
  • PathwayCatecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2.
  • Involvement in diseaseDefects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) [MIM:608643]. AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.
  • Sequence similaritiesBelongs to the group II decarboxylase family.

    • Target information above from: UniProt accession P20711 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    see all
  • Alternative names
      AADC antibodyAromatic L Amino Acid Decarboxylase antibodyAromatic-L-amino-acid decarboxylase antibody
      DDC antibodyDDC protein antibodyDDC_HUMAN antibodyDOPA decarboxylase (aromatic L-amino acid decarboxylase) antibodyDOPA decarboxylase antibody
    see all

Anti-DOPA Decarboxylase antibody images

References for Anti-DOPA Decarboxylase antibody (ab32587)

ab32587 has not yet been referenced specifically in any publications.

Publishing research using ab32587 ? Please let us know so that we can cite the reference in this datasheet

Product Wall

Submit an Abreview for ab32587 Submit a Question for ab32587

Displaying 1 - 1 of 1 results for Abreviews and Q&A

10
Votes: Highest First

I bought your ab32587 today. I am just wondering whether you have the IgG concentration of this antibody. I am trying to run a IHC using it.

Thank you for your enquiry. Regarding ab32587, I apologize that I can only offer you a range in which to expect the concentration to fall. This product is not formulated based solely on concentration. The signal strength (in QC-WB) is a much more ind...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"