Anti-DOPA Decarboxylase antibody (ab32587)

Overview

  • Product nameAnti-DOPA Decarboxylase antibodySee all DOPA Decarboxylase primary antibodies ...
  • Description
    Rabbit polyclonal to DOPA Decarboxylase
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Rat, Sheep, Rabbit, Guinea pig, Cow, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to amino acids from the N terminus of DOPA Decarboxylase (Human) conjugated to KLH.

  • Positive control
    • Bovine adrenal medulla lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab32587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 55 kDa (predicted molecular weight: 54 kDa).

Target

  • FunctionCatalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
  • PathwayCatecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2.
  • Involvement in diseaseDefects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) [MIM:608643]. AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.
  • Sequence similaritiesBelongs to the group II decarboxylase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • AADC antibody
    • Aromatic L Amino Acid Decarboxylase antibody
    • Aromatic-L-amino-acid decarboxylase antibody
    • DDC antibody
    • DDC protein antibody
    • DDC_HUMAN antibody
    • DOPA decarboxylase (aromatic L-amino acid decarboxylase) antibody
    • DOPA decarboxylase antibody
    see all

Anti-DOPA Decarboxylase antibody images

References for Anti-DOPA Decarboxylase antibody (ab32587)

ab32587 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Regarding ab32587, I apologize that I can only offer you a range in which to expect the concentration to fall. This product is not formulated based solely on concentration. The signal strength (in QC-WB) is a much more ...

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