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Read our guarantee »Products:Neuroscience >> Neurotransmitter >> Biogenic Amines >> Dopamine
Anti-DOPA Decarboxylase antibody
See all DOPA Decarboxylase products (8) ...
Rabbit polyclonal to DOPA Decarboxylase
Reacts with
Rat, Sheep, Rabbit, Guinea pig, Cow, Dog, Human
Synthetic peptide corresponding to amino acids from the N terminus of DOPA Decarboxylase (Human) conjugated to KLH.
Bovine adrenal medulla lysate.
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: None
Constituents: 50% Glycerol, 100µg/ml BSA, 150mM Sodium chloride, 10mM HEPES. pH 7.5
Concentration information loading...
Immunogen affinity purified
Polyclonal
IgG
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Hormone biosynthesis
Neuroscience >> Neurotransmitter >> Biogenic Amines >> Dopamine
Western blot - DOPA Decarboxylase antibody (ab32587)
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Our Abpromise guarantee covers the use of ab32587 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000Detects a band of approximately 55 kDa (predicted molecular weight: 54 kDa).
Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2.
Defects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) [MIM:608643]. AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.
Belongs to the group II decarboxylase family.
Target information above from: UniProt accessionP20711
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Western blot - DOPA Decarboxylase antibody (ab32587)
Anti-DOPA Decarboxylase antibody (ab32587) at 1/1000 dilution + bovine adrenal medulla lysate at 5 µg
Predicted band size : 54 kDa
Observed band size : 55 kDa (why is the actual band size different from the predicted?)
ab32587 has not yet been referenced specifically in any publications.
Publishing research using ab32587? Please let us know so that we can cite the reference in this datasheet
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Anti-DOPA Decarboxylase antibody (ab32587) at 1/1000 dilution + bovine adrenal medulla lysate at 5 µg
Predicted band size : 54 kDa
Observed band size : 55 kDa (why is the actual band size different from the predicted?)
0
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