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Western blot - DPM3 antibody (ab23422)
(enlarge)
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Product Name
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DPM3 antibody
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Product type
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Primary antibodies
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Description
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Goat polyclonal to DPM3
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Immunogen
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Synthetic peptide: QEARADLARRGLRF, corresponding to C terminal amino acids 79-92 of Human DPM3.
BLAST 'QEARADLARRGLRF' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms
(Due to sequence homology)
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 20 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human Liver extracts.
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Cellular localization
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Integral membrane protein. Endoplasmic reticulum.
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Research areas
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Signal Transduction >> Protein Trafficking >> ER Proteins
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Relevance
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Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. DPM3 is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris buffered saline. pH 7.3 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this DPM3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for DPM3 antibody images, references, products related to ab23422 and other tools.
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DPM3 antibody images:
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Search PubMed (MEDLINE) for references to DPM3
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DPM3 antibody - more information
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Customer reviews (feedback) regarding DPM3 antibody |
Customer FAQs regarding DPM3 antibody |
Protocols for DPM3 antibody |
Price and availability of products related to DPM3 antibody |
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DPM3 antibody - related products:
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DPM3 antibody - other tools:
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Contact Abcam with a Technical Enquiry about DPM3 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
Western blot - DPM3 antibody (ab23422)