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Anti-DPM3 antibody (ab23422)

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Overview

Product name

Anti-DPM3 antibody

Description

Goat polyclonal to DPM3

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse

Immunogen

Synthetic peptide: QEARADLARRGLRF, corresponding to C terminal amino acids 79-92 of Human DPM3.

QEARADLARR GLRF

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Human Liver extracts.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris buffered saline. pH 7.3

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Protein Trafficking >> ER Proteins

  • Western blot - DPM3 antibody (ab23422)Western blot - DPM3 antibody (ab23422) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab23422 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. DPM3 is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex.

Cellular localization

Integral membrane protein. Endoplasmic reticulum.

Alternative names

  • Dolichol Phosphate Mannose Synthase subunit 3 antibody
  • Dolichyl Phosphate beta D Mannosyltransferase subunit 3 antibody
  • Mannose P Dolichol Synthase subunit 3 antibody
  • Prostin 1 antibody

Database links

see all

Anti-DPM3 antibody images:

  Western blot - DPM3 antibody (ab23422)

Western blot - DPM3 antibody (ab23422)

Anti-DPM3 antibody (ab23422) at 1 µg/ml (Identification of DPM3 in human liver extracts with 35ug protein per lane and a primary antibody incubation of 1 hour.)

Observed band size : 20 kDa (why is the actual band size different from the predicted?)

References for Anti-DPM3 antibody (ab23422)

ab23422 has not yet been referenced specifically in any publications.

Publishing research using ab23422? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"