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Products:Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes
Overview
Product name
Anti-DPP10 antibody
See all DPP10 products (7) ...
Description
Goat polyclonal to DPP10
Specificity
ab31292 recognises Dipeptidylpeptidase 10.
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Chicken, Cow, Dog, Chimpanzee
Immunogen
Synthetic peptide: C-DEGHNVSEKSKYHL, corresponding to Internal sequence amino acids 765-779 of Human DPP10
C-DEGHNVSE KSKYHL
Positive control
Human Bone Marrow lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality
Polyclonal
Isotype
IgG
Research areas
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Serine protease >> DPPs
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes
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Western blot - DPP10 antibody (ab31292)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab31292 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.1 - 0.3 µg/ml.Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa).
ELISA
ELISA: 1/32000ELISA: 1/32000
Target
Function
Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2.
Tissue specificity
Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands.
Involvement in disease
Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
Sequence similarities
Belongs to the peptidase S9B family. DPPIV subfamily.
Post-translational
modifications
N-glycosylated.
Cellular localization
Membrane.
Target information above from: UniProt accessionQ8N608
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Dipeptidyl peptidase like protein 2 antibody
- DPPY antibody
- Dipeptidyl peptidase 10 antibody
see all
Database links
- Entrez Gene: 617222 Cow
- Entrez Gene: 476121 Dog
- Entrez Gene: 57628 Human
- Omim: 608209 Human
- SwissProt: Q8N608 Human
- Unigene: 176247 Human
- Unigene: 591555 Human
Anti-DPP10 antibody images:
Western blot - DPP10 antibody (ab31292)
Anti-DPP10 antibody (ab31292) at 0.1 µg/ml (incubation time: 1 hour) + Human Bone Marrow lysate (35µg protein in RIPA buffer)
developed using the ECL technique
Predicted band size : 90 kDa
Observed band size : 90 kDa
References for Anti-DPP10 antibody (ab31292)
ab31292 has not yet been referenced specifically in any publications.
Publishing research using ab31292? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"