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Products:Neuroscience >> Neurology process >> Neural Signal Transduction
Overview
Product name
Anti-Dab1 antibody
See all Dab1 products (7) ...
Description
Goat polyclonal to Dab1
Tested applications
WB, IPmore details
Cross reactivity
Reacts with
Mouse
Immunogen
Fusion protein, corresponding to amino acids 1-179 of Mouse Dab1.
Positive control
293 cells transfected with Dab1–HA tag IP. Dab1 Knockout brain p14 lysate and Dab1 Wild Type brain p14 lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.08% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Adapters
Neuroscience >> Neurology process >> Neural Signal Transduction
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Western blot - Dab1 antibody (ab16674)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab16674 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml.Detects a band of approximately 80 kDa (predicted molecular weight: 67 kDa).
IP: Use a concentration of 5 - 10 µg/ml.
Target
Function
Adapter molecule functioning in neural development. May regulate SIAH1 activity.
Sequence similarities
Contains 1 PID domain.
Domain
The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
Post-translational
modifications
Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
Target information above from: UniProt accessionO75553
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Dab 1 antibody
- Dab1 antibody
- DAB1_HUMAN antibody
see all
Database links
- Entrez Gene: 13131 Mouse
- SwissProt: P97318 Mouse
- Unigene: 289682 Mouse
Anti-Dab1 antibody images:
Western blot - Dab1 antibody (ab16674)
Predicted band size : 67 kDa
ab16674 detecting mouse Dab1 in brain extracts by Western blot.
Lane 1: ab16674 (N terminal).
Lane 2: ab16675 (C terminal).
References for Anti-Dab1 antibody (ab16674)
ab16674 has not yet been referenced specifically in any publications.
Publishing research using ab16674? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"