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Products:Neuroscience >> Neurology process >> Neurogenesis
Overview
Product name
Dact1 / Dapper homolog 1 peptide
See all Dact1 / Dapper homolog 1 products (3) ...
Protein description
Synthetic peptide derived from within residues 550 - 650 of Mouse Dact1 / Dapper homolog 1.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab42380 - Dact1 / Dapper homolog 1 antibody.
Protein length
778 amino acids
Properties
Purity
70 - 90% by HPLC
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Stem Cells >> Signaling Pathways >> Wnt >> Cytoplasmic
Neuroscience >> Neurology process >> Neurogenesis
Applications
Application notes
This peptide can be used with studies using ab42380.
Protein info
Function
Positively regulates DVL2-mediated signaling pathways during development. Binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
Sequence similarities
Belongs to the dapper family.
Domain
The C-terminal PDZ-binding motif mediates interaction with the PDZ domains of DSH (Dishevelled) family proteins.
Cellular localization
Cytoplasm. Nucleus.
Target information above from: UniProt accessionQ9NYF0
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for Dact1 / Dapper homolog 1 peptide (ab42379)
ab42379 has not yet been referenced specifically in any publications.
Publishing research using ab42379? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"