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Overview

  • Product nameDact1 / Dapper homolog 1 peptideSee all Dact1 / Dapper homolog 1 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 500 - 600 of Human Dact1 / Dapper homolog 1.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab42547 - Dact1 / Dapper homolog 1 antibody.
  • Protein length836 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab42547.

    • Protein info

    • Alternative names
        DactDact1DACT1_HUMAN
        DapperDapper antagonist of beta catenin homolog 1Dapper antagonist of catenin 1Dapper homolog 1DAPPER1DprDpr1FrdFrodohDPR1Hepatocellular carcinoma novel gene 3 proteinHeptacellular carcinoma novel gene 3HNG3MTNG3Thyex3
      see all
  • FunctionPositively regulates DVL2-mediated signaling pathways during development. Binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
  • Sequence similaritiesBelongs to the dapper family.
  • DomainThe C-terminal PDZ-binding motif mediates interaction with the PDZ domains of DSH (Dishevelled) family proteins.
  • Cellular localizationCytoplasm. Nucleus.

    • Target information above from: UniProt accession Q9NYF0 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Dact1 / Dapper homolog 1 peptide (ab42546)

    ab42546 has not yet been referenced specifically in any publications.

    Publishing research using ab42546 ? Please let us know so that we can cite the reference in this datasheet

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