Overview

  • Product nameAnti-DcR1 antibody [B-D44]
    See all DcR1 primary antibodies
  • Description
    Mouse monoclonal [B-D44] to DcR1
  • Tested applicationsFlow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant DcR1/Fc chimera (Human)

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 1% BSA, PBS
  • Concentration information loading...
  • PurityIon Exchange Chromatography
  • Clonality Monoclonal
  • Clone numberB-D44
  • Myelomax63-Ag8.653
  • IsotypeIgG1
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab46849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use 10µl for 106 cells or 100 µl of whole blood.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceDcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
    • Cellular localizationCell Membrane and Cytoplasmic
    • Database links
    • Alternative names
      • Antagonist decoy receptor for TRAIL/Apo 2L antibody
      • CD263 antibody
      • Cytotoxic TRAIL receptor 3 antibody
      • DCR1 antibody
      • DCR1 TNFR antibody
      • Decoy Receptor 1 antibody
      • Decoy TRAIL receptor without death domain antibody
      • LIT antibody
      • Lymphocyte inhibitor of TRAIL antibody
      • MGC149501 antibody
      • MGC149502 antibody
      • TNF related apoptosis inducing ligand receptor 3 antibody
      • TNF-re ated apoptosis inducing ligand receptor 3 antibody
      • TNFRSF10C antibody
      • TRAIL R3 antibody
      • TRAIL receptor 3 antibody
      • TRAILR3 antibody
      • TRID antibody
      • Tumor necrosis factor receptor superfamily member 10C antibody
      • Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain antibody
      see all

    References for Anti-DcR1 antibody [B-D44] (ab46849)

    This product has been referenced in:
    • Mérino D  et al. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol 26:7046-55 (2006). Read more (PubMed: 16980609) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"