Overview
Product nameDcR1 peptideSee all DcR1 proteins and peptides ...
Properties
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.2
Concentration information loading...
Additional notesStable for one year.
Sequence notesCKEGTFRNENSPE
Amino acids 111-123 of human DcR1
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab6096
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
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Notes |
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Application notesThe peptide is used for blocking the antibody activity of anti- DcR1 (cat.no 2087). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37°C.
Protein info
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Alternative names
Antagonist decoy receptor for TRAIL/Apo 2LCD263Cytotoxic TRAIL receptor 3
DcR 1DCR1DCR1 TNFRDecoy Receptor 1Decoy TRAIL receptor without death domainLITLymphocyte inhibitor of TRAILMGC149501MGC149502TNF Related Apoptosis Inducing Ligand Receptor 3TNF-re ated apoptosis inducing ligand receptor 3TNFRSF10CTRAIL R3TRAIL receptor 3TRAIL Receptor Without An Intracellular DomainTRAILR3TRIDTumor Necrosis Factor Receptor Superfamily Member 10CTumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
see all
RelevanceDcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
Cellular localizationCell Membrane and Cytoplasmic
References for DcR1 peptide (ab6096)
ab6096
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
