Overview

  • Product nameAnti-Decorin antibody [3H4-1F4]See all Decorin primary antibodies ...
  • Description
    Mouse monoclonal [3H4-1F4] to Decorin
  • Tested applicationsELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein Human Decorin with a proprietary tag (AAH05322)

  • Positive control
    • Human breast tissue; Human soft tissue; Decorin transfected 293T cell lysate; Recombinant Decorin protein

Properties

Applications

Our Abpromise guarantee covers the use of ab115744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent dilution. Predicted molecular weight: 40 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionMay affect the rate of fibrils formation.
  • Involvement in diseaseDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
  • Sequence similaritiesBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
    Contains 12 LRR (leucine-rich) repeats.
  • Post-translational
    modifications
    The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bone proteoglycan II antibody
    • CSCD antibody
    • DCN antibody
    • DCN protein antibody
    • Decorin antibody
    • Decorin proteoglycan antibody
    • Dermatan sulphate proteoglycans II antibody
    • DKFZp686J19238 antibody
    • DSPG 2 antibody
    • DSPG2 antibody
    • PG 40 antibody
    • PG II antibody
    • PG S2 antibody
    • PG-S2 antibody
    • PG40 antibody
    • PGII antibody
    • PGS 2 antibody
    • PGS2 antibody
    • PGS2_HUMAN antibody
    • Proteoglycan core protein antibody
    • SLRR1B antibody
    • Small leucine rich protein 1B antibody
    see all

Anti-Decorin antibody [3H4-1F4] images

  • ab115744 at 5ug/ml staining Decorin in Human breast tissue by immunohistochemistry (FFPE).
  • ab115744 at 5ug/ml staining Decorin in Human soft tissue by immunohistochemistry (FFPE).
  • All lanes : Anti-Decorin antibody [3H4-1F4] (ab115744)

    Lane 1 : Decorin transfected 293T cell lysate
    Lane 2 : Non-transfected control


    Predicted band size : 40 kDa
  • ab115744 binding to recombinant Decorin by ELISA. Detection limit for recombinant tagged Decorin is approximately 1 ng/ml as a capture antibody.

References for Anti-Decorin antibody [3H4-1F4] (ab115744)

ab115744 has not yet been referenced specifically in any publications.

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