Anti-Decorin antibody [3H4-1F4] (ab115744)

Overview

• Product nameAnti-Decorin antibody [3H4-1F4]See all Decorin primary antibodies ...
• Description
  Mouse monoclonal [3H4-1F4] to Decorin
• Tested applicationsELISA, WB, IHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length protein Human Decorin with a proprietary tag (AAH05322)

• Positive controlHuman breast tissue; Human soft tissue; Decorin transfected 293T cell lysate; Recombinant Decorin protein

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferpH: 7.20
  Constituent: 99% PBS
• Concentration information loading...
• PurityProtein A purified
• Clonality Monoclonal
• Clone number3H4-1F4
• IsotypeIgG2b
• Light chain typekappa
• Research Areas
  • Stem Cells
  • Mesenchymal Stem Cells
  • Osteogenesis

  • Signal Transduction
  • Cytoskeleton / ECM
  • Extracellular Matrix
  • Structures
  • Bone

  • Signal Transduction
  • Cytoskeleton / ECM
  • Extracellular Matrix
  • ECM Proteins
  • Collagen

Applications

Target

• FunctionMay affect the rate of fibrils formation.
• Involvement in diseaseDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
• Sequence similaritiesBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
  Contains 12 LRR (leucine-rich) repeats.
• Post-translational
  modificationsThe attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
• Cellular localizationSecreted > extracellular space > extracellular matrix.

Target information above from: UniProt accession P07585 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 1634 Human
  • Omim: 125255 Human
  • SwissProt: P07585 Human
  • Unigene: 728830 Human

• Alternative names
  Bone proteoglycan II antibodyCSCD antibodyDCN antibody

  DCN protein antibodyDecorin antibodyDecorin proteoglycan antibodyDermatan sulphate proteoglycans II antibodyDKFZp686J19238 antibodyDSPG 2 antibodyDSPG2 antibodyPG 40 antibodyPG II antibodyPG S2 antibodyPG-S2 antibodyPG40 antibodyPGII antibodyPGS 2 antibodyPGS2 antibodyPGS2_HUMAN antibodyProteoglycan core protein antibodySLRR1B antibodySmall leucine rich protein 1B antibody

  see all

Anti-Decorin antibody [3H4-1F4] images

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Decorin antibody [3H4-1F4] (ab115744)
  ab115744 at 5ug/ml staining Decorin in Human breast tissue by immunohistochemistry (FFPE).
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Decorin antibody [3H4-1F4] (ab115744)
  ab115744 at 5ug/ml staining Decorin in Human soft tissue by immunohistochemistry (FFPE).
• 

  Western blot - Anti-Decorin antibody [3H4-1F4] (ab115744)
  All lanes : Anti-Decorin antibody [3H4-1F4] (ab115744)
  
  Lane 1 : Decorin transfected 293T cell lysate
  Lane 2 : Non-transfected control
  
  
  Predicted band size : 40 kDa
  
• 

  ELISA - Anti-Decorin antibody [3H4-1F4] (ab115744)
  ab115744 binding to recombinant Decorin by ELISA. Detection limit for recombinant tagged Decorin is approximately 1 ng/ml as a capture antibody.