Anti-Deptor antibody (ab103298)
Key features and details
- Rabbit polyclonal to Deptor
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-Deptor antibody
See all Deptor primary antibodies -
Description
Rabbit polyclonal to Deptor -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant full length protein within Human Deptor aa 1-450. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- Mouse liver tissue lysate; Deptor transfected 293T cell line
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab103298 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 46 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 46 kDa. |
Target
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Function
Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. -
Sequence similarities
Contains 2 DEP domains.
Contains 1 PDZ (DHR) domain. -
Post-translational
modificationsPhosphorylated. Phosphorylation weakens interaction with MTOR within mTORC1 and mTORC2. - Information by UniProt
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Database links
- Entrez Gene: 64798 Human
- Entrez Gene: 97998 Mouse
- Omim: 612974 Human
- SwissProt: Q8TB45 Human
- SwissProt: Q570Y9 Mouse
- Unigene: 112981 Human
- Unigene: 295397 Mouse
- Unigene: 393497 Mouse
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Alternative names
- DEP domain containing 6 antibody
- DEP domain-containing mTOR-interacting protein antibody
- DEP domain-containing protein 6 antibody
see all
Images
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Anti-Deptor antibody (ab103298) at 1/500 dilution + Mouse liver tissue lysate at 50 µg
Predicted band size: 46 kDa -
All lanes : Anti-Deptor antibody (ab103298) at 1/500 dilution
Lane 1 : Deptor transfected 293T cell line lysate
Lane 2 : non transfected 293T cell line lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 46 kDa
Datasheets and documents
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Datasheet download
References (0)
ab103298 has not yet been referenced specifically in any publications.