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Overview

  • Product nameDexras1 protein (Tagged-His Tag)See all Dexras1 proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to amino acids 104-281 of Human Dexras1 with N terminal His tag; 178 amino acids, 26kDa (20kDa predicted from sequence). UniProt ID = Q9Y272
  • Expression hostE. coli

    • Properties

  • Purification notesPurity level >85%
    This protein was expressed as an N-terminal His-tag fusion protein using Escherichia coli, and purified using Immobilized Metal Ion Affinity Chromatography. In some cases, smaller protein fragments may be present in addition to the intended expression product as a result of premature termination during translation in E. coli and subsequent co-purification via the His-tag. In some cases purified proteins run at a molecular weight different to the theoretically calculated molecular weight. This may be as a result of unequally distributed charges in the amino acid sequence. Alternatively, dimerisation of the expression product can occur under oxygen limitation during expression/cultivation.
  • FormLyophilised:Reconstitute with 91 µl aqua dest.
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
  • Concentration information loading...
  • Additional notesProtein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch).
  • Sequence notesSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVIC GNKGDRDFYREVDQREIEQ LVGDDPQRCAYFEISAKKN SSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKA LRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDL MYIREKASAGSQAKDKERCVIS
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab91818 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE
    MS
  • Application notesMS: Use at an assay dependent dilution.
    SDS-PAGE: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        Activator of G protein signalingActivator of G protein signaling 1Activator of G-protein signaling 1
        AGS 1AGS1Dexamethasone induced ras related protein 1Dexamethasone-induced ras protein 1Dexamethasone-induced Ras-related protein 1Dexras 1MGC:26290RAS dexamethasone induced 1Ras protein, Dexamethasone-induced, 1Ras related proteinRASD 1RASD1RASD1_HUMAN
      see all
  • FunctionSmall GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65.
  • Tissue specificityExpressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues.
  • Sequence similaritiesBelongs to the small GTPase superfamily. RasD family.
  • Post-translational
    modifications    S-nitrosylation stimulates guanine-nucleotide exchange activity.
  • Cellular localizationCell membrane. Cytoplasm > perinuclear region. Nucleus.

    • Target information above from: UniProt accession Q9Y272 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Dexras1 protein (Tagged-His Tag) images

    • SDS-PAGE - Dexras1 protein (Tagged-His Tag) (ab91818)
      SDS-PAGE - Dexras1 protein (Tagged-His Tag) (ab91818)
      The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

    References for Dexras1 protein (Tagged-His Tag) (ab91818)

    ab91818 has not yet been referenced specifically in any publications.

    Publishing research using ab91818 ? Please let us know so that we can cite the reference in this datasheet

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