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Immunoprecipitation - Diazepam Binding Inhibitor antibody [20B10] (ab16775)
![Immunoprecipitation - Diazepam Binding Inhibitor antibody [20B10] (ab16775)](/ps/datasheet/images/ab16775_1.jpg)
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Product Name
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Diazepam Binding Inhibitor antibody [20B10]
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See all Diazepam Binding Inhibitor antibodies (3)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [20B10] to Diazepam Binding Inhibitor
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Immunogen
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Fusion protein (Human DBI).
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Reacts with
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Hu
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Does not react with
(species key)
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Ms, Rat
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Tested applications
(see key)
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ELISA, IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
IP: Use at a concentration of 1 - 2 µg/ml lysate.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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HepG2 whole cell lysate.
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Research areas
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Neuroscience >> Neuropharmacology >> Molecular Neuropharmacology
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
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Relevance
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Diazepam Binding Inhibitor(DBI) is a highly conserved 10kDa polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central and peripheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer disease.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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20B10
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.03% Sodium Azide
Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Diazepam Binding Inhibitor antibody [20B10] is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for Diazepam Binding Inhibitor antibody [20B10] images, references, products related to ab16775 and other tools.
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Diazepam Binding Inhibitor antibody [20B10] images:
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 Immunoprecipitation - Diazepam Binding Inhibitor antibody [20B10] (ab16775)
Immunoprecipitation analysis of HepG2 cell lysates using ab16775.
Lane 1: Input.
Lane 2: Precipitates.
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Search PubMed (MEDLINE) for references to Diazepam Binding Inhibitor
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Diazepam Binding Inhibitor antibody [20B10] - more information
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Customer reviews (feedback) regarding Diazepam Binding Inhibitor antibody [20B10] |
Customer FAQs regarding Diazepam Binding Inhibitor antibody [20B10] |
Protocols for Diazepam Binding Inhibitor antibody [20B10] |
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Diazepam Binding Inhibitor antibody [20B10] - related products:
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Diazepam Binding Inhibitor antibody [20B10] - other tools:
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Contact Abcam with a Technical Enquiry about Diazepam Binding Inhibitor antibody [20B10] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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