![Western blot - Diazepam Binding Inhibitor antibody [27C9] (ab16806) image](#ab16806_1.jpg)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Diazepam Binding Inhibitor antibody [27C9] (ab16806) image](#Diazepam-Binding-Inhibitor-Primary-antibodies-ab16806-5.jpg)
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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Overview
Product name
Anti-Diazepam Binding Inhibitor antibody [27C9]
See all Diazepam Binding Inhibitor products (3) ...
Description
Mouse monoclonal [27C9] to Diazepam Binding Inhibitor
Tested applications
ELISA, WB, IP, IHC-Pmore details
Cross reactivity
Reacts with
Human
Does not react with
Mouse, Rat
Immunogen
Fusion protein (Human DBI) purified from E.coli.
Positive control
HepG2 whole cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 50% Glycerol, PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Monoclonal
Clone number
27C9
Isotype
IgG2b
Light chain type
kappa
Research areas
Neuroscience >> Neuropharmacology >> Molecular Neuropharmacology
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab16806 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
- 1 Image
WB
IP
Application notes
ELISA: Use at an assay dependent dilution.
IP: Use at a concentration of 1 - 2 µg/ml lysate.
WB: 1/100 - 1/500. Predicted molecular weight: 10 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Tissue specificity
Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.
Sequence similarities
Belongs to the ACBP family.
Contains 1 ACB (acyl-CoA-binding) domain.
Target information above from: UniProt accessionP07108
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ACBD 1 antibody
- ACBD1 antibody
- ACBP antibody
see all
Database links
- Entrez Gene: 1622 Human
- Omim: 125950 Human
- SwissProt: P07108 Human
- Unigene: 78888 Human
Anti-Diazepam Binding Inhibitor antibody [27C9] images:
Western blot - Diazepam Binding Inhibitor antibody [27C9] (ab16806)
![Western blot - Diazepam Binding Inhibitor antibody [27C9] (ab16806)](/ps/datasheet/Images/16/ab16806/ab16806_1.jpg)
Predicted band size : 10 kDa
ab16806 at a 1/500 dilution staining approx. 10kDa Diazepam binding inhibitor in HepG2 cell lysate by Western blot (ECL).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Diazepam Binding Inhibitor antibody [27C9] (ab16806)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Diazepam Binding Inhibitor antibody [27C9] (ab16806)](/ps/datasheet/images/16/ab16806/Diazepam-Binding-Inhibitor-Primary-antibodies-ab16806-5.jpg)
IHC-P image of Diazepam Binding Inhibitor antibody (ab16806) on Lung cancer sections. The sections were fixed in Paraformaldehyde and underwent heat mediated antigen retrieval using Novacastra (pH6). The sections were then blocked in 3% H2O2 solution for 10 minutes at 22°C.
Aamir Ahmed, University College London, United Kingdom.
References for Anti-Diazepam Binding Inhibitor antibody [27C9] (ab16806)
ab16806 has not yet been referenced specifically in any publications.
Publishing research using ab16806? Please let us know so that we can cite the reference in this datasheet
![Diazepam Binding Inhibitor antibody [27C9] for Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) in Human (16806)](/ps/datasheet/images/16/ab16806/Diazepam-Binding-Inhibitor-Primary-antibodies-ab16806-4.jpg)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"