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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Overview
Product name
Anti-Diazepam Binding Inhibitor antibody
See all Diazepam Binding Inhibitor products (3) ...
Description
Rabbit polyclonal to Diazepam Binding Inhibitor
Specificity
We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Fusion protein (Human DBI).
Positive control
U87MG whole cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.03% Sodium Azide
Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neuropharmacology >> Molecular Neuropharmacology
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
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Western blot - Diazepam Binding Inhibitor antibody (ab16871)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab16871 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000Predicted molecular weight: 10 kDa.
Target
Function
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Tissue specificity
Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.
Sequence similarities
Belongs to the ACBP family.
Contains 1 ACB (acyl-CoA-binding) domain.
Target information above from: UniProt accessionP07108
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ACBD 1 antibody
- ACBD1 antibody
- ACBP antibody
see all
Database links
- Entrez Gene: 1622 Human
- Omim: 125950 Human
- SwissProt: P07108 Human
- Unigene: 78888 Human
Anti-Diazepam Binding Inhibitor antibody images:
Western blot - Diazepam Binding Inhibitor antibody (ab16871)
Predicted band size : 10 kDa
ab16871 at 1/1000 dilution staining human Diazepam Binding Inhibitor in U87MG cell lysate by Western blot.
References for Anti-Diazepam Binding Inhibitor antibody (ab16871)
ab16871 has not yet been referenced specifically in any publications.
Publishing research using ab16871? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"